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Call for papers: The future of pragmatic trials

Edited by: Prof Marion Campbell and Prof Sandra Eldridge

Trials invites you to submit articles for our new thematic series on “The future of pragmatic trials”.

The Editors will consider articles that report on current understandings of the role and definition of the pragmatic design (including comparative effectiveness research and real world trials), its use and applicability to modern-day healthcare challenges, its relevance to and use with novel trial designs (e.g. cohort multiple, stepped wedge, cluster randomized, registry trials), and considerations of ethical issues (e.g. streamlined research ethics review, patient engagement, different types of consent).

We encourage articles on any topic relevant to the role, definition and use of the pragmatic trial design.  Commentaries and opinion pieces are welcome, especially those looking explicitly to the future use of the pragmatic design. All articles should make explicit and clear the relevance to pragmatic trials and how the results or opinions in the article should be used to improve our understanding and use of the design in the future.

Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. In the submission system please make sure the correct collection title is chosen from the additional information tab. Please also indicate clearly in the covering letter that the manuscript is to be considered in the ‘The future of pragmatic trials” series.

For further information, please use the contact us email on the journal website.

  1. Content type: Research

    Delirium is an acute mental disorder and common postoperative complication. Monitoring regional cerebral oxygen saturation (rSO2) in endovascular therapeutic surgery may allow real-time monitoring of cerebral des...

    Authors: Xiaohua Wang, Kunpeng Feng, Haixia Liu, Yanhui Liu, Ming Ye, Guoguang Zhao and Tianlong Wang

    Citation: Trials 2019 20:504

    Published on:

  2. Content type: Study protocol

    Both-bone forearm fractures are a common fracture, accounting for 3.4% of all paediatric fractures. For now, elastic stable intramedullary nailing (ESIN) and open reduction and internal fixation (ORIF) are the...

    Authors: Chunhui Chen, Linzhen Xie, Wenhao Zheng, Hua Chen and Leyi Cai

    Citation: Trials 2019 20:320

    Published on:

  3. Content type: Research

    Intravenous (IV) iron is frequently used to treat iron deficiency/anemia in patients who are unable to tolerate oral iron or the oral iron is not sufficient toreplete iron requirements. However, safety concern...

    Authors: Ahmed Ziedan and Sunil Bhandari

    Citation: Trials 2019 20:194

    Published on: