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Selected articles in Fetal and Developmental Exposure for PPTOX 2018

New Content Item (1)The environment at fetal and early postnatal development stages is of crucial importance for gene expression and can affect development and disease risks through to adult life. During these vulnerable stages, the timing of exposure and the related gene-environment interactions are key. The PPToxVI conference, taking place in May, aims to assess the weight of evidence and highlight new achievements on the effects of prenatal and early postnatal exposure to toxicants, as well their effects on the development.

This article collection from Environmental Health showcases the top accessed articles recently published in the journal relating to fetal and developmental exposure. Articles in this collection were selected by the Editor's in Chief Prof Philippe Grandjean and Prof David Ozonoff.

  1. Glyphosate (GLY) is the most heavily used herbicide worldwide but the extent of exposure in human pregnancy remains unknown. Its residues are found in the environment, major crops, and food items that humans, ...

    Authors: S. Parvez, R. R. Gerona, C. Proctor, M. Friesen, J. L. Ashby, J. L. Reiter, Z. Lui and P. D. Winchester
    Citation: Environmental Health 2018 17:23
  2. Prenatal exposure to persistent organic pollutants (POPs), may influence offspring weight gain. More prospective epidemiological studies are needed to compliment the growing body of evidence from animal studies.

    Authors: Hilde B. Lauritzen, Tricia L. Larose, Torbjørn Øien, Torkjel M. Sandanger, Jon Ø. Odland, Margot van de Bor and Geir W. Jacobsen
    Citation: Environmental Health 2018 17:9
  3. Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposu...

    Authors: Nynke Spinder, Jorieke E. H. Bergman, H. Marike Boezen, Roel C. H. Vermeulen, Hans Kromhout and Hermien E. K. de Walle
    Citation: Environmental Health 2017 16:83
  4. Air pollution is involved in many pathologies. These pollutants act through several mechanisms that can affect numerous physiological functions, including reproduction: as endocrine disruptors or reactive oxyg...

    Authors: Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud and Roger Léandri
    Citation: Environmental Health 2017 16:82
  5. Prenatal and postnatal exposure to bisphenol A (BPA) may affect early brain development. Rodent studies suggest that prenatal and postnatal neurodevelopmental toxicity from BPA exposure may manifest as social ...

    Authors: Youn-Hee Lim, Sanghyuk Bae, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim and Yun-Chul Hong
    Citation: Environmental Health 2017 16:79
  6. Vaginal candidiasis is frequent among pregnant women and it is treated with anti-fungal medication (conazoles). Conazoles have anti-androgenic properties and prenatal exposure in rodents is associated with a s...

    Authors: Djamilla Madelung Mogensen, Maria Bergkvist Pihl, Niels E. Skakkebæk, Helle Raun Andersen, Anders Juul, Henriette Boye Kyhl, Shanna Swan, David Møbjerg Kristensen, Marianne Skovager Andersen, Dorte Vesterholm Lind and Tina Kold Jensen
    Citation: Environmental Health 2017 16:68
  7. Environmental exposures and immune conditions during pregnancy could influence development of autism spectrum disorder (ASD) in offspring. However, few studies have examined immune-triggering exposures in rela...

    Authors: Alison B. Singer, Igor Burstyn, Malene Thygesen, Preben Bo Mortensen, M. Daniele Fallin and Diana E. Schendel
    Citation: Environmental Health 2017 16:31
  8. Children are exposed to flame retardants from the built environment. Brominated diphenyl ethers (BDE) and organophosphate-based flame retardants (OPFRs) are associated with poorer neurocognitive functioning in...

    Authors: Shannon T. Lipscomb, Megan M. McClelland, Megan MacDonald, Andres Cardenas, Kim A. Anderson and Molly L. Kile
    Citation: Environmental Health 2017 16:23
  9. National data suggest widespread gestational exposure to organophosphate pesticides (OPs) based on the detection of OP metabolites in the urine of pregnant women. Associations with early infant neurobehavior a...

    Authors: Kimberly Yolton, Yingying Xu, Heidi Sucharew, Paul Succop, Mekibib Altaye, Ann Popelar, M Angela Montesano, Antonia M Calafat and Jane C Khoury
    Citation: Environmental Health 2013 12:79