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Post-operative pain control

Guest Editors:
Aboud AlJa'bari: University of Jordan, Jordan
Lalit Gupta: Maulana Azad Medical College & Lok Nayak Hospital, India
Mihai Popescu: Fundeni Clinical Institute & Carol Davila University of Medicine and Pharmacy, Romania
Giustino Varrassi: Paolo Procacci Foundation, Italy



BMC Anesthesiology has published a topical collection on “Post-operative pain control” to highlight new research in this field focusing on novel analgesics, multimodal anesthesia and regional anesthesia making the step to a personalized post-operative pain control. Post-operative pain control is a major factor of modern anesthesia care. Recent advances, such as multimodal analgesia, regional anesthesia techniques and opioid free anesthesia have significantly impacted the way we care for our patients in the perioperative period and has impacted patient comfort and satisfaction. Moreover, considering increasing age of patients addressed for surgery, as well as the high incidence of severe co-morbidities, providing safe anesthesia care in terms of post-operative management has become a crucial aspect of modern anesthesia practice.

Meet the Guest Editors

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Aboud AlJa'bari: University of Jordan, Jordan

Prof. Aboud AlJa’bari did his fellowship in France and Switzerland in Cardiothoracic anaesthesia as well as in Regional anaesthesia and Pain Medicine, and he is now a Consultant in Cardiothoracic, Regional Anaesthesia and Pain Medicine. Prof. AlJa’bari has published more than 30 articles in well-known anaesthesia journals, and he has also been an international speaker in anaesthesia conferences like ESRA. His research interests focus on anaesthesia for all varieties of surgeries.

Lalit Gupta: Maulana Azad Medical College & Lok Nayak Hospital, India

Dr. Lalit Gupta is working as Associate Professor in the Anaesthesiology and Intensive care department at Maulana Azad Medical College and Associated Hospitals, New Delhi, India. He has more than 17 years of experience in the field of Anaesthesia and Intensive care, and has authored the books "Synopsis of Anaesthesia" and "Drugs in Anaesthesia and Critical Care". He is also an Instructor and provider for Acute Critical Care Management course (ACCM). Dr. Gupta has special Interest in Intensive Care, Remote area-anaesthesia management, Difficult airway, Onco-anaesthesia, Pain medicine and palliative care.

Mihai Popescu: Fundeni Clinical Institute & Carol Davila University of Medicine and Pharmacy, Romania

Mihai Popescu is an Associate Professor of Anaesthesia and Critical Care at “Carol Davila” University of Medicine and Pharmacy in Bucharest, Romania and also an international examiner for EDAIC. His main areas of interest are perioperative medicine, anaesthesia for major abdominal surgery, thoracic surgery and liver transplantation, acute liver failure, sepsis and extracorporeal organ support. He is currently involved in active research on topics such as regional anaesthesia for major liver resections, opioid-free anaesthesia and liver support therapies. 

Giustino Varrassi: Paolo Procacci Foundation, Italy

Prof. Varrassi is the President of the Paolo Procacci Foundation, an NGO based in Rome and involved in research and education on Pain Medicine. He started his academic career in the Department of Anaesthesiology and Intensive Care of the University of Rome. He later became Chairman of the Anaesthesiology and Pain Medicine Department at the University of L'Aquila, Italy. Prof. Varrassi has started and directed all the Academic Anaesthesia and Pain Medicine programs at the University of L'Aquila.

About the collection

Post-operative pain control is a major factor of modern anesthesia care. Recent advances, such as multimodal analgesia, regional anesthesia techniques and opioid free anesthesia have significantly impacted the way we care for our patients in the perioperative period and has impacted patient comfort and satisfaction. Moreover, considering increasing age of patients addressed for surgery, as well as the high incidence of severe co-morbidities, providing safe anesthesia care in terms of perioperative management has become a crucial aspect of modern anesthesia practice.

Choosing one technique for pain control over another has become challenging and objective assessment of pain severity is still a debatable issue. In this context, perioperative pain medicine has become more complex than ever and, hence it has evolved into a new branch of perioperative medicine comprising of new insights on advanced monitoring, pharmacology and neurophysiology. 

BMC Anesthesiology has published a topical collection on “Post-operative pain control” focusing on new research in this field focusing on novel analgesics, multimodal anesthesia and regional anesthesia making the step to a personalized perioperative pain control.

This collection comprises submissions from all aspects of this field including, but not limited to:

•    Novel analgesics: new approaches to pain management, such as the development of novel analgesics, including non-opioid medications, and new routes of administration, such as transdermal and intranasal.
•    Multimodal anaesthesia: The use of a combination of medications to provide pain relief after surgery, including local anaesthetics, opioids, and non-opioid analgesics, as well as non-pharmacological techniques such as nerve blocks, and cognitive behavioural therapy.
•    Regional anaesthesia: The use of nerve blocks, epidurals, and other regional anaesthesia techniques to provide targeted pain relief after surgery.
•    Personalized perioperative pain control: The use of patient-specific factors, such as age, comorbidities, and genetic variations, to individualize pain management plans.
•    Postoperative pain assessment: Advances in pain assessment techniques and tools, including the use of patient-reported outcomes and wearable devices.
•    Pharmacogenomics: The use of genetic information to optimize pain management by identifying medications that are most effective and safe for individual patients.
•    Economic impact: The economic impact of improved pain management, including reductions in healthcare costs, length of hospital stays, and readmissions.
•    Pain assessment: research on new methods of measuring pain and assessing the effectiveness of pain management strategies.

Image credit: © sebastianosecondi / Getty Images / iStock

  1. Thoracotomy procedures can result in significant pain and cause nausea/vomiting. Glucocorticoids have anti-emetic and analgesic effects due to their anti-inflammatory and nerve-blocking properties. This study ...

    Authors: Hamid Talebzadeh, Mohammad Eslamian, Erfan Sheikhbahaei, Ali Esparham, Hamidreza Zefreh, Pooria Sarblook and Alireza Firouzfar
    Citation: BMC Anesthesiology 2024 24:240
  2. Ultrasound-guided transversus abdominis plane (TAP) block is commonly used for pain control in laparoscopic cholecystectomy. However, significant pain persists, affecting patient recovery and sleep quality on ...

    Authors: Jung-Pil Yoon, Hee Young Kim, Jieun Jung, Jimin Lee, Seyeon Park and Gyeong-Jo Byeon
    Citation: BMC Anesthesiology 2024 24:203
  3. The Erector spinae plane block (ESPB) reduces postoperative pain after several types of abdominal laparoscopic surgeries. There is sparse data on the effect of ESPB in laparoscopic ventral hernia repair. The p...

    Authors: Marie Sørenstua, Johan Ræder, Jan Sverre Vamnes and Ann-Chatrin Linqvist Leonardsen
    Citation: BMC Anesthesiology 2024 24:192
  4. Although the efficacy and safety of epidural block (EB) are fairly high, complications such as inadvertent dural puncture may limit its use. Ultrasound-guided quadratus lumborum block (QLB) is a relatively new...

    Authors: Mohamed Wageh, Mohamed Ahmed Sultan, Hazem El Sayed Moawad, Ehab Mohamed Mokbel and Mahmoud Mohammed Alseoudy
    Citation: BMC Anesthesiology 2024 24:180
  5. There is a sizable niche for a minimally invasive analgesic technique that could facilitate ambulatory video-assisted thoracoscopic surgery (VATS). Our study aimed to determine the analgesic potential of a sin...

    Authors: A. Clairoux, A. Moore, M. Caron-Goudreault, M. Soucy-Proulx, M. Thibault, V. Brulotte, ME. Bélanger, J. Raft, N. Godin, M. Idrissi, J. Desroches, M. Ruel, A. Fortier and P. Richebé
    Citation: BMC Anesthesiology 2024 24:156
  6. Evidence regarding the potentiating effects of intravenous dexamethasone on peripheral regional anesthesia in children is sparse. The objective of the current study was to investigate the potentiating effect o...

    Authors: Sonia Ben Khalifa, Ahmed Ben Slimene, Hajer Blaiti, Refka Kaddour, Amjed Fekih Hassen, Pierre Pardessus, Christopher Brasher and Souhayl Dahmani
    Citation: BMC Anesthesiology 2024 24:145
  7. The Wide-Awake Local Anesthesia No Tourniquet (WALANT) technique allows intraoperative motor assessment of tendon repair integrity of the hand compared with general anesthesia or brachial plexus block. No stud...

    Authors: Mahmoud Mohammed Alseoudy, Elsayed Mohamed Abdelkarime, Khaled Nour and May Elsherbiny Badr
    Citation: BMC Anesthesiology 2024 24:120
  8. The pupillary response to tetanic electrical stimulation reflects the balance between nociceptive stimulation and analgesia. Although pupillary pain index (PPI) was utilized to predict postoperative pain, it d...

    Authors: Huang Huang, Yinuo Qiu, Guoxin Gu, Xiangyang Mei, Liwei Pang, Chuangxin Zhang, Mingzi Ran and Mengmeng Li
    Citation: BMC Anesthesiology 2024 24:61
  9. Cleft palate repair surgery may result in severe pain in the immediate postoperative period. The aim of this study is to compare the effects of different doses of nalbuphine for postoperative analgesia in chil...

    Authors: Zhan-ming Chen, Bao-hua Gao and Liang-shan Wang
    Citation: BMC Anesthesiology 2024 24:22
  10. Although video-assisted thoracoscopic surgery (VATS) has advantages of reduced injury and faster healing, patients still endure moderate and severe postoperative pain. Paracetamol and mannitol injection, the f...

    Authors: Yin Zhou, Peng Yuan, Qi Xing, Wenjie Jin and Chonglong Shi
    Citation: BMC Anesthesiology 2024 24:14
  11. Total knee arthroplasty (TKA) is a common orthopedic procedure for end-stage knee osteoarthritis. Although effective in relieving pain and improving function, postoperative pain is still a common and distressi...

    Authors: An Chen, Wanqing Duan, Ruijinlin Hao, Chen Wang and Xingguo Xu
    Citation: BMC Anesthesiology 2023 23:400

    The Correction to this article has been published in BMC Anesthesiology 2023 23:421

  12. This study aims to estimate the safety, efficacy, and median effective dose (ED50) of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy.

    Authors: Zhongling Xu, Yantao Lang, Xiaolei Xu, Linjuan Deng, Hengya Song and Dekun Yin
    Citation: BMC Anesthesiology 2023 23:385
  13. Postoperative pain is one of the most common complications after surgery. In order to detect early and intervene in time for moderate to severe postoperative pain, it is necessary to identify risk factors and ...

    Authors: Gaoxiang Shi, Geliang Liu, Qichao Gao, Shengxiao Zhang, Qi Wang, Li Wu, Peifeng He and Qi Yu
    Citation: BMC Anesthesiology 2023 23:361
  14. There are limited real-world data regarding the use of droperidol for antiemetic prophylaxis in intravenous patient-controlled analgesia (IV-PCA). This study aimed to evaluate the antiemetic benefits and sedat...

    Authors: Jia Qi Tan, Hsiang-Ling Wu, Yi-Chien Wang, Juan P. Cata, Jui-Tai Chen, Yih-Giun Cherng and Ying-Hsuan Tai
    Citation: BMC Anesthesiology 2023 23:351
  15. National guidelines for rational opioid prescribing for acute postoperative pain are needed to optimise postoperative pain control and function whilst minimising opioid-related harm.

    Authors: C. L. McCorquodale, R. Greening, R. Tulloch and P. Forget
    Citation: BMC Anesthesiology 2023 23:294
  16. The application of artificial intelligence patient-controlled analgesia (AI-PCA) facilitates the remote monitoring of analgesia management, the implementation of mobile ward rounds, and the automatic recording...

    Authors: Di Wang, Yihui Guo, Qian Yin, Hanzhong Cao, Xiaohong Chen, Hua Qian, Muhuo Ji and Jianfeng Zhang
    Citation: BMC Anesthesiology 2023 23:281
  17. Surgery to repair pectus excavatum (PE) is often associated with severe postoperative pain, which can impact the length of hospital stay (LOS). While thoracic epidural analgesia (TEA) has traditionally been us...

    Authors: Li-Jung Chen, Shih-Hong Chen, Yung-Lin Hsieh and Po-Chuan Yu
    Citation: BMC Anesthesiology 2023 23:266

Submission Guidelines

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This Collection welcomes submission of Research Articles. Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select ["Post-operative pain control"] from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.