Edited by Andrea Boggild (MD), University of Toronto, Canada
The interplay between a given protozoan or metazoan parasite and the host's immune response to that infection directly influences the clinical manifestations of disease, the detectability of the parasite on standard diagnostic testing, and the efficacy of treatment and control strategies. Given the breadth and complexity of parasite taxa, the host-parasite interactions that can occur are manifold. The manifestations of many such parasitic infections are worsened by congenital and acquired causes of host immune suppression, such as immunosuppressant drugs like corticosteroids, or immunosuppressing infections like HIV.
That we, as a medical and scientific establishment, are becoming increasingly able to suppress the host's immune system - due to the confluence of economic, social, and technological factors - translates into increasing opportunities to both trigger and rectify such deleterious host-parasite interactions. With the globalization of both infectious diseases and immunosuppressing interventions like solid-organ transplant and biologic therapy, humans parasitized by a range of protozoan and metazoan infections are increasingly intersecting this nascent capacity in areas unaccustomed to handling both. Collectively, then, we have an opportunity and obligation to better illuminate the underpinnings of host-parasite interactions, and to strive towards not just treating but preventing the attributable clinical fallout.
Aims and Scope
We herein invite submissions to a theme issue of Tropical Diseases, Travel Medicine, and Vaccines entitled "Parasitic Diseases and Immunosuppression", which aims to address some of the current knowledge gaps in this area. Case reports, case series, perspective pieces, original articles, and reviews addressing any aspect of parasitic interactions with an immunosuppressed host are welcome.
The series is now closed for further submissions.
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The Editor has no competing interests with the submissions which are handled through the peer review process. The peer review of any submissions for which the Editor has competing interests is handled by another Editorial Board Member who has no competing interests.