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Evolving understanding of the biology of pain and its application to patient care

Daniel Clauw and Anthony Jones

  1. Review

    Placebo analgesia: cognitive influences on therapeutic outcome

    The therapeutic response to a drug treatment is a mixture of direct pharmacological action and placebo effect. Therefore, harnessing the positive aspects of the placebo effect and reducing the negative ones co...

    Alison Watson, Andrea Power, Christopher Brown, Wael El-Deredy and Anthony Jones

    Arthritis Research & Therapy 2012 14:206

    Published on: 30 March 2012

  2. Review

    The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia

    Pain is a key component of most rheumatologic diseases. In fibromyalgia, the importance of central nervous system pain mechanisms (for example, loss of descending analgesic activity and central sensitization) ...

    Yvonne C Lee, Nicholas J Nassikas and Daniel J Clauw

    Arthritis Research & Therapy 2011 13:211

    Published on: 28 April 2011

  3. Review

    Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines

    The peripheral nociceptor is an important target of pain therapy because many pathological conditions such as inflammation excite and sensitize peripheral nociceptors. Numerous ion channels and receptors for i...

    Hans-Georg Schaible, Andrea Ebersberger and Gabriel Natura

    Arthritis Research & Therapy 2011 13:210

    Published on: 28 April 2011