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Non-Total Joint Arthroplasty: Alternative Option for Knee Osteoarthritis Treatment

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With the growth of the aging population, the number of patients with knee osteoarthritis (KOA) has been increasing each year. Total knee replacement (TKR) is an effective treatment for KOA. However, it is an ultimate treatment with a limited indication for the very end stage of KOA. For patients with earlier stages (Kellgren-Lawrence grade 2 or 3) with progressive symptoms, effective surgical treatments were historically lacking. Notably, knee-preserving osteotomy and UKA have made great progress in terms of technology and market size in recent years, and received more and more attention in the world.

To consolidate the latest knowledge and philosophy of knee preservation surgeries and demonstrate the latest techniques and procedures related to these methods, we announce a Special Issue "Non-Total Joint Arthroplasty: Alternative Option for Knee Osteoarthritis Treatment". This research topic provides an open platform to display new ideas and insights into knee-preserving osteotomy and UKA, from basic etiology research to cutting-edge clinical research. We encourage researchers to submit their constructive suggestions and innovations to promote the continuous development of all knee preservative surgeries. We welcome original research/clinical articles, comments, and opinions on potential topics. The thesis includes but is not limited to:

  • Basic research investigating of the UKA or knee-preserving osteotomy, includes biomechanics, kinematics, or finite element analysis.
  • Clinical outcome of UKA or knee-preserving osteotomy and related techniques.
  • Cutting-edge work of knee preservation surgery with advanced techniques such as navigation, robot, 3D printing, and AI.


This is a cross-journal collection published in Arthroplasty and Knee Surgery & Related Research.

  1. Authors: Vitantonio Digennaro, Riccardo Ferri, Alessandro Panciera, Barbara Bordini, Davide Cecchin, Lorenzo Benvenuti, Francesco Traina and Cesare Faldini
    Citation: Knee Surgery & Related Research 2024 36:14
  2. This systematic review aimed to evaluate the effects of concurrent cartilage procedures on cartilage regeneration when performed alongside high tibial osteotomy (HTO).

    Authors: Joo Hyung Han, Min Jung, Kwangho Chung, Se-Han Jung, Chong-Hyuk Choi and Sung-Hwan Kim
    Citation: Knee Surgery & Related Research 2024 36:13
  3. Although intraoperative navigation can improve the surgeon’s proficiency, no studies have analyzed postoperative outcomes of high tibial osteotomy (HTO) after computer-assisted surgery (CAS) experience. The pr...

    Authors: Sang Jun Song, Dae Kyung Bae, Se Hwan Park and Cheol Hee Park
    Citation: Knee Surgery & Related Research 2023 35:29
  4. Unicompartmental knee arthroplasty (UKA) is an effective surgical treatment for medial compartment arthritis of the knee, yet surgical outcomes are directly related to surgical execution. Robotic arm-assisted ...

    Authors: Matthew H. Y. Yeung, Henry Fu, Amy Cheung, Vincent Chan Wai Kwan, Man Hong Cheung, Ping Keung Chan, Kwong Yuen Chiu and Chun Hoi Yan
    Citation: Arthroplasty 2023 5:55