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Opportunities and risks of nanomaterials (NRP 64)

Opportunities and risks for human health and the environment in relation to the manufacture, use and disposal of synthetic nanomaterials need to be better understood.

The National Research Programme "Opportunities and Risks of Nanomaterials" (NRP 64) hopes to be able to bridge the gaps in our current knowledge on nanomaterials.

Publication charges for this collection were funded by the Swiss National Science
Foundation. Articles have undergone the journal’s standard peer-review process.

  1. Research

    Effects of silica nanoparticle exposure on mitochondrial function during neuronal differentiation

    Nanomedicine offers a promising tool for therapies of brain diseases, but potential effects on neuronal health and neuronal differentiation need to be investigated to assess potential risks. The aim of this st...

    Angélique D. Ducray, Andrea Felser, Jana Zielinski, Aniela Bittner, Julia V. Bürgi, Jean-Marc Nuoffer, Martin Frenz and Meike Mevissen

    Journal of Nanobiotechnology 2017 15:49

    Published on: 4 July 2017

  2. Review

    Non-invasive continuous monitoring of pro-oxidant effects of engineered nanoparticles on aquatic microorganisms

    Engineered nanomaterials (ENMs) are key drivers for the development of highly sophisticated new technologies. As all new attainments, the rapidly increasing used of ENMs raise concerns about their safety for t...

    Christian Santschi, Nadia Von Moos, Volodymyr B. Koman, Vera I. Slaveykova, Paul Bowen and Olivier J. F. Martin

    Journal of Nanobiotechnology 2017 15:19

    Published on: 7 March 2017

  3. Review

    Transformation of the released asbestos, carbon fibers and carbon nanotubes from composite materials and the changes of their potential health impacts

    Composite materials with fibrous reinforcement often provide superior mechanical, thermal, electrical and optical properties than the matrix. Asbestos, carbon fibers and carbon nanotubes (CNTs) have been widel...

    Jing Wang, Lukas Schlagenhauf and Ari Setyan

    Journal of Nanobiotechnology 2017 15:15

    Published on: 20 February 2017

  4. Review

    Interaction of biomedical nanoparticles with the pulmonary immune system

    Engineered nanoparticles (NPs) offer site-specific delivery, deposition and cellular uptake due to their unique physicochemical properties and were shown to modulate immune responses. The respiratory tract wit...

    Fabian Blank, Kleanthis Fytianos, Emilie Seydoux, Laura Rodriguez-Lorenzo, Alke Petri-Fink, Christophe von Garnier and Barbara Rothen-Rutishauser

    Journal of Nanobiotechnology 2017 15:6

    Published on: 9 January 2017

  5. Review

    A critical review of the current knowledge regarding the biological impact of nanocellulose

    Several forms of nanocellulose, notably cellulose nanocrystals and nanofibrillated cellulose, exhibit attractive property matrices and are potentially useful for a large number of industrial applications. Thes...

    C. Endes, S. Camarero-Espinosa, S. Mueller, E. J. Foster, A. Petri-Fink, B. Rothen-Rutishauser, C. Weder and M. J. D. Clift

    Journal of Nanobiotechnology 2016 14:78

    Published on: 1 December 2016

  6. Research

    Release of copper-amended particles from micronized copper-pressure-treated wood during mechanical abrasion

    We investigated the particles released due to abrasion of wood surfaces pressure-treated with micronized copper azole (MCA) wood preservative and we gathered preliminary data on its in vitro cytotoxicity for l...

    Chiara Civardi, Lukas Schlagenhauf, Jean-Pierre Kaiser, Cordula Hirsch, Claudio Mucchino, Adrian Wichser, Peter Wick and Francis W. M. R. Schwarze

    Journal of Nanobiotechnology 2016 14:77

    Published on: 28 November 2016

  7. Research

    Lipid nanoemulsions and liposomes improve photodynamic treatment efficacy and tolerance in CAL-33 tumor bearing nude mice

    Photodynamic therapy (PDT) as promising alternative to conventional cancer treatments works by irradiation of a photosensitizer (PS) with light, which creates reactive oxygen species and singlet oxygen (1O2), tha...

    Doris Hinger, Susanna Gräfe, Fabrice Navarro, Bernhard Spingler, Devaraj Pandiarajan, Heinrich Walt, Anne-Claude Couffin and Caroline Maake

    Journal of Nanobiotechnology 2016 14:71

    Published on: 3 October 2016

  8. Research

    Photoinduced effects of m-tetrahydroxyphenylchlorin loaded lipid nanoemulsions on multicellular tumor spheroids

    Photosensitizers are used in photodynamic therapy (PDT) to destruct tumor cells, however, their limited solubility and specificity hampers routine use, which may be overcome by encapsulation. Several promising...

    Doris Hinger, Fabrice Navarro, Andres Käch, Jean-Sébastien Thomann, Frédérique Mittler, Anne-Claude Couffin and Caroline Maake

    Journal of Nanobiotechnology 2016 14:68

    Published on: 7 September 2016

  9. Research

    Vertical transport and plant uptake of nanoparticles in a soil mesocosm experiment

    Agricultural soils represent a potential sink for increasing amounts of different nanomaterials that nowadays inevitably enter the environment. Knowledge on the relation between their actual exposure concentra...

    Alexander Gogos, Janine Moll, Florian Klingenfuss, Marcel van der Heijden, Fahmida Irin, Micah J. Green, Renato Zenobi and Thomas D. Bucheli

    Journal of Nanobiotechnology 2016 14:40

    Published on: 8 June 2016

  10. Research

    Effect of nanoparticles on red clover and its symbiotic microorganisms

    Nanoparticles are produced and used worldwide and are released to the environment, e.g., into soil systems. Titanium dioxide (TiO2) nanoparticles (NPs), carbon nanotubes (CNTs) and cerium dioxide (CeO2) NPs are a...

    Janine Moll, Alexander Gogos, Thomas D. Bucheli, Franco Widmer and Marcel G. A. van der Heijden

    Journal of Nanobiotechnology 2016 14:36

    Published on: 10 May 2016

  11. Research

    Probabilistic modelling of prospective environmental concentrations of gold nanoparticles from medical applications as a basis for risk assessment

    The use of gold nanoparticles (Au-NP) based medical applications is rising due to their unique physical and chemical properties. Diagnostic devices based on Au-NP are already available in the market or are in ...

    Indrani Mahapatra, Tian Yin Sun, Julian R. A. Clark, Peter J. Dobson, Konrad Hungerbuehler, Richard Owen, Bernd Nowack and Jamie Lead

    Journal of Nanobiotechnology 2015 13:93

    Published on: 22 December 2015

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