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Molecular Neurodegeneration: Novel Systems and Emerging Concepts

The 4th International Conference on Molecular Neurodegeneration (ICMN2016), held in Seoul, Republic of Korea, May 11-13 2016, gathered more than 300 participants from all over the world. In 14 scientific sessions including oral and poster presentations as well as panel discussions scientific progress under the theme ‘Novel Systems and Emerging Concepts’ was discussed. 

In this article collection, published by Molecular Neurodegeneration, the state-of-the-art scientific developments presented during the meeting are reviewed.

  1. Tauopathies are a broad set of neurodegenerative dementias characterized by aggregation of the tau protein into filamentous inclusions that can be found in neurons and glial cells. Activated microglia, astrocy...

    Authors: Cheryl E. G. Leyns and David M. Holtzman
    Citation: Molecular Neurodegeneration 2017 12:50
  2. Abnormal aggregation of tau in the brain is a major contributing factor in various neurodegenerative diseases. The role of tau phosphorylation in the pathophysiology of tauopathies remains unclear. Consequentl...

    Authors: Laure Saint-Aubert, Laetitia Lemoine, Konstantinos Chiotis, Antoine Leuzy, Elena Rodriguez-Vieitez and Agneta Nordberg
    Citation: Molecular Neurodegeneration 2017 12:19
  3. Alzheimer’s disease (AD) transgenic mice have been used as a standard AD model for basic mechanistic studies and drug discovery. These mouse models showed symbolic AD pathologies including β-amyloid (Aβ) plaqu...

    Authors: Se Hoon Choi, Young Hye Kim, Luisa Quinti, Rudolph E. Tanzi and Doo Yeon Kim
    Citation: Molecular Neurodegeneration 2016 11:75