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The 4th International Conference on Molecular Neurodegeneration (ICMN2016) held in Seoul Korea May 11-13 2016 gathered more than 300 participants from all over the world. In 14 scientific sessions including oral and poster presentations as well as panel discussions scientific progress under the theme ‘Novel Systems and Emerging Concepts’ was discussed.
In this article collection, published by Molecular Neurodegeneration, the state-of-the-art scientific developments presented during the meeting are reviewed.
Review
Tauopathies are a broad set of neurodegenerative dementias characterized by aggregation of the tau protein into filamentous inclusions that can be found in neurons and glial cells. Activated microglia, astrocy...
Molecular Neurodegeneration 2017 12:50
Published on: 29 June 2017
Review
Abnormal aggregation of tau in the brain is a major contributing factor in various neurodegenerative diseases. The role of tau phosphorylation in the pathophysiology of tauopathies remains unclear. Consequentl...
Molecular Neurodegeneration 2017 12:19
Published on: 20 February 2017
Review
Alzheimer’s disease (AD) transgenic mice have been used as a standard AD model for basic mechanistic studies and drug discovery. These mouse models showed symbolic AD pathologies including β-amyloid (Aβ) plaqu...
Molecular Neurodegeneration 2016 11:75
Published on: 9 December 2016
Review
Over the past 20 years, substantial progress has been made in identifying the underlying genetics of Parkinson’s disease (PD). Of the known genes, LRRK2 is a major genetic contributor to PD. However, the exact...
Molecular Neurodegeneration 2016 11:73
Published on: 7 December 2016
