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Roles of microRNAs and other noncoding RNAs in cancer

  1. PIWI-interacting RNAs (piRNAs) are a large family of small, single-stranded, non-coding RNAs present throughout the animal kingdom. They form complexes with several members of the PIWI clade of Argonaute prote...

    Authors: Miguel Moyano and Giovanni Stefani
    Citation: Journal of Hematology & Oncology 2015 8:38
  2. Since recent studies revealed the feasibility to detect blood-based microRNAs (miRNAs, miRs) in breast cancer (BC) patients a new field has been opened for circulating miRNAs as potential biomarkers in BC. In ...

    Authors: Thalia Erbes, Marc Hirschfeld, Gerta Rücker, Markus Jaeger, Jasmin Boas, Severine Iborra, Sebastian Mayer, Gerald Gitsch and Elmar Stickeler
    Citation: BMC Cancer 2015 15:193
  3. Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes. lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through recruitment of chromatin modifiers. The expr...

    Authors: Gregory Loewen, Janarthanan Jayawickramarajah, Ying Zhuo and Bin Shan
    Citation: Journal of Hematology & Oncology 2014 7:90
  4. Since the discovery of circulating microRNAs (miRNAs) in body fluids, an increasing number of studies have focused on their potential as non-invasive biomarkers and as therapeutic targets or tools for many dis...

    Authors: Wen-Tao Wang and Yue-Qin Chen
    Citation: Journal of Hematology & Oncology 2014 7:86
  5. While microRNAs (miRNAs) and the KRAS oncogene are known to be dysregulated in various cancers, little is known about the role of miRNAs in the regulation of KRAS in cancer. Here we review a selection of studies ...

    Authors: Minlee Kim and Frank J Slack
    Citation: Journal of Hematology & Oncology 2014 7:84