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Collection on Non-coding RNAs

Molecular and cellular biology of noncoding RNA molecules has become one of the fastest growing research fields in science and also in medical practice and technology. There are numerous communications concerning miRNA, lncRNA and circRNA which have been published (especially in the last two years) in Cellular & Molecular Biology Letters. We present this collection of some of our recent publications on this topic and hope it will inspire you to submit your own work to be included in this collection.

Submit your research on non-coding RNAs here.

Articles in this collection:

  2. More powerful prognostic and diagnostic tools are urgently needed for identifying and treating ovarian cancer (OC), which is the most fatal malignancy in women in developed countries. Circular RNAs (circRNAs) ...

    Authors: Zahra Foruzandeh, Fatemeh Zeinali-Sehrig, Kazem Nejati, Dara Rahmanpour, Fariba Pashazadeh, Farhad Seif and Mohammad Reza Alivand
    Citation: Cellular & Molecular Biology Letters 2021 26:41
    Content type: Review Letter Published on:

  3. Iron overload can promote the development of osteoporosis by inducing apoptosis in osteoblasts. However, the mechanism by which miRNAs regulate apoptosis in osteoblasts under iron overload has not been elucida...

    Authors: Yi Feng, Pei-Yan He, Wei-Dong Kong, Wan-Jing Cen, Peng-Lin Wang, Chang Liu, Wu Zhang, Shu-Shu Li and Jian-Wei Jiang
    Citation: Cellular & Molecular Biology Letters 2021 26:37
    Content type: Research Letter Published on:

  4. Long noncoding RNA (lncRNA), urothelial carcinoma-associated 1 (UCA1) is aberrantly expressed in multiple cancers and has been verified as an oncogene. However, the underlying mechanism of UCA1 in the developm...

    Authors: An Yang, Xin Liu, Ping Liu, Yunzhang Feng, Hongbo Liu, Shen Gao, Limin Huo, Xinyan Han, Jurong Wang and Wei Kong
    Citation: Cellular & Molecular Biology Letters 2021 26:33
    Content type: Research Published on:

  6. Diabetic nephropathy is one of the most important complications in patients with diabetes. The etiology and pathogenesis of diabetic nephropathy remain unclear. Several studies have indicated that circular RNA...

    Authors: Xuan Xiong, Changchun Liu, Meiren Shen, Qian Yang, Qiang Zhao, Xiaoyan Li, Xiaoshi Zhong and Zhiwei Wang
    Citation: Cellular & Molecular Biology Letters 2021 26:25
    Content type: Research Letter Published on:

  7. The suppressive effects of miR-33a-5p have been reported in colorectal cancer and lung cancer. However, the functional role of miR-33a-5p in pancreatic ductal adenocarcinoma (PDAC) has not yet been elucidated.

    Authors: Yanfen Lian, Dongxiao Jiang and Jiangtao Sun
    Citation: Cellular & Molecular Biology Letters 2021 26:24
    Content type: Research Published on:

  8. Improved chondrogenic differentiation of mesenchymal stem cells (MSCs) by genetic regulation is a potential method for regenerating articular cartilage. MiR-127-5p has been reported to promote cartilage differ...

    Authors: Xiaozhong Zhou, Wangyang Xu, Yeyang Wang, Hui Zhang, Li Zhang, Chao Li, Shun Yao, Zixiang Huang, Lishan Huang and Dixin Luo
    Citation: Cellular & Molecular Biology Letters 2021 26:22
    Content type: Research Published on:

  9. Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signal...

    Authors: Qiudan Chen, Weifeng Wang, Shuying Chen, Xiaotong Chen and Yong Lin
    Citation: Cellular & Molecular Biology Letters 2021 26:21
    Content type: Research Letter Published on:

  11. The expression signature of deregulated long non-coding RNAs (lncRNAs) and related genetic variants is implicated in every stage of tumorigenesis, progression, and recurrence. This study aimed to explore the a...

    Authors: Shahad W. Kattan, Yahya H. Hobani, Sameerah Shaheen, Sara H. Mokhtar, Mohammad H. Hussein, Eman A. Toraih, Manal S. Fawzy and Hussein Abdelaziz Abdalla
    Citation: Cellular & Molecular Biology Letters 2021 26:14
    Content type: Research Published on:

  12. ZNF674-AS1, a recently characterized long noncoding RNA, shows prognostic significance in hepatocellular carcinoma and glioma. However, the expression and function of ZNF674-AS1 in non-small cell lung cancer (...

    Authors: Yu Liu, Risheng Huang, Deyao Xie, Xiaoming Lin and Liangcheng Zheng
    Citation: Cellular & Molecular Biology Letters 2021 26:6
    Content type: Research Published on:

  13. miRNAs are well known to be gene repressors. A newly identified class of miRNAs termed nuclear activating miRNAs (NamiRNAs), transcribed from miRNA loci that exhibit enhancer features, promote gene expression ...

    Authors: Emmanuel Odame, Yuan Chen, Shuailong Zheng, Dinghui Dai, Bismark Kyei, Siyuan Zhan, Jiaxue Cao, Jiazhong Guo, Tao Zhong, Linjie Wang, Li Li and Hongping Zhang
    Citation: Cellular & Molecular Biology Letters 2021 26:4
    Content type: Review Published on:

  14. To explore the effect of miR-296-5p on the metastasis of nasopharyngeal carcinoma (NPC) cells and investigate the underlying mechanism.

    Authors: Meihui Chen, Chen Chen, Haiqing Luo, Jing Ren, Qiuqin Dai, Wenjia Hu, Keyuan Zhou, Xudong Tang and Xiangyong Li
    Citation: Cellular & Molecular Biology Letters 2020 25:49
    Content type: Research Published on:

  15. Circular RNAs (circRNAs) are thought to be involved in the development of various malignancies. The expression and function of hsa_circ_0006916, a newly identified circRNA, in hepatocellular carcinoma remain u...

    Authors: Xiao-Yong Zhou, Hui Yang, Yang-Qiu Bai, Xiu-Ling Li, Shuang-Yin Han and Bing-Xi Zhou
    Citation: Cellular & Molecular Biology Letters 2020 25:47
    Content type: Research Published on:

  16. Long intergenic non-protein coding RNA00665 (LINC00665) plays a crucial tumorigenic role in many cancers, such as gastric cancer and lung adenocarcinoma. However, its role and mechanism of action in the progre...

    Authors: Minhao Lv, Qixin Mao, Juntao Li, Jianghua Qiao, Xiuchun Chen and Suxia Luo
    Citation: Cellular & Molecular Biology Letters 2020 25:43
    Content type: Research Published on:

  17. Animal model studies show that reductive stress is involved in cardiomyopathy and myopathy, but the exact physiological relevance remains unknown. In addition, the microRNAs miR-143 and miR-145 have been shown...

    Authors: Kota Ogawa, Akiko Noda, Jun Ueda, Takehiro Ogata, Rumiko Matsuyama, Yuji Nishizawa, Shanlou Qiao, Satoru Iwata, Morihiro Ito, Yoshitaka Fujihara, Masatoshi Ichihara, Koichi Adachi, Yuji Takaoka and Takashi Iwamoto
    Citation: Cellular & Molecular Biology Letters 2020 25:40
    Content type: Research Published on:

  19. Dysregulation of the proliferation and migration of vascular smooth muscle cells (VSMCs) is a crucial cause of atherosclerosis. MiR-637 exerts an antiproliferative effect on multiple human cells. Its impact on...

    Authors: Ning Yang, Bo Dong, Yanqiu Song, Yang Li, Lu Kou, Jingyu Yang and Qin Qin
    Citation: Cellular & Molecular Biology Letters 2020 25:30
    Content type: Research Letter Published on:

  20. Long non-coding RNA (lncRNA) as a widespread and pivotal epigenetic molecule participates in the occurrence and progression of malignant tumors. DRAIC, a kind of lncRNA whose coding gene location is on 15q23 c...

    Authors: Zheng Zhang, Xiaoxuan Hu, Jia Kuang, Jinmao Liao and Qi Yuan
    Citation: Cellular & Molecular Biology Letters 2020 25:29
    Content type: Research Published on:

  21. MicroRNA dysregulation occurs in many human diseases, including atherosclerosis. Here, we examined the serum expression and clinical significance of miR-186-5p in patients with atherosclerosis, and explored it...

    Authors: Bin Sun, Qingtao Cao, Meng Meng and Xiaolong Wang
    Citation: Cellular & Molecular Biology Letters 2020 25:27
    Content type: Research Letter Published on:

  22. Oxidative stress results in cell apoptosis/death and plays a detrimental role in disease development and progression. Stressors alter the miRNA expression profile and miRNAs play a role in the cell response to...

    Authors: Duo Zhao, Hao Zheng, Adam Greasley, Fengjun Ling, Qinfeng Zhou, Bowen Wang, Tiffany Ni, Ishita Topiwala, Cuilin Zhu, Tina Mele, Kexiang Liu and Xiufen Zheng
    Citation: Cellular & Molecular Biology Letters 2020 25:26
    Content type: Research Published on:

  24. Pulmonary arterial hypertension (PAH) is often characterized by cell proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs). LncRNA cancer susceptibility candidate 2 (CASC2) has been re...

    Authors: Yan Han, Yuhao Liu, Chaokuan Yang, Chuanyu Gao, Xiaoyan Guo and Jiangtao Cheng
    Citation: Cellular & Molecular Biology Letters 2020 25:21
    Content type: Research Published on:

  25. It has been shown that miR-144-3p regulates cell proliferation, apoptosis, migration and invasion in various cancers. However, the function and expression of miR-144-3p in colorectal cancer (CRC) remained obsc...

    Authors: Naihui Sun, Liang Zhang, Chongguang Zhang and Yuan Yuan
    Citation: Cellular & Molecular Biology Letters 2020 25:19
    Content type: Research Published on:

  26. MicroRNA-125b (miR-125b) is downregulated in human cutaneous squamous cell carcinoma (CSCC). However, its function in CSCC has yet to be extensively explored. Here, we analyze the relationship between signal t...

    Authors: Ke Tian, Wanggen Liu, Jing Zhang, Xiaoyi Fan, Jingyuan Liu, Nan Zhao, Chunxia Yao and Guoying Miao
    Citation: Cellular & Molecular Biology Letters 2020 25:12
    Content type: Research Letter Published on:

  27. Viral myocarditis (VMC) is a type of cardiac inflammation that is generally caused by coxsackievirus B3 (CVB3) infection. Several MicroRNAs (miRNAs) are known to play crucial roles in VMC pathogenesis. MiR-15 ...

    Authors: Ru Tong, Tiewen Jia, Ruijie Shi and Futang Yan
    Citation: Cellular & Molecular Biology Letters 2020 25:6
    Content type: Research Published on:

  28. MicroRNAs (miRNAs or miRs) can participate in the development and progression of neuroblastoma. Many studies have indicated that miR-429 can participate in tumor development. However, the mechanism underlying ...

    Authors: Xianjun Zhou, Hongting Lu, Fujiang Li, Xiwei Hao, Lulu Han, Qian Dong and Xin Chen
    Citation: Cellular & Molecular Biology Letters 2020 25:5
    Content type: Research Published on: