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Nanosensors: Their potential use in the life sciences and clinical medicine

Here we present a special issue of J Nanobiotechnology on nanosensors in a rather broad sense, focusing on two questions: (1) why study nanosensors; and (2) what according their potential use in the life sciences and, more specifically, in medicine might be.

Recently, there have been significant advances in this area of research, with many of the studies not even explicitly using the term “nanosensor”. Some of these may have led to novel findings harboring great potential for clinical medicine such as, for example, the early detection/diagnosis of diseases or minimally invasive local treatments/interventions.

The special issue illustrates a diverse range of technologies using nanomaterials and nanoparticles such as graphene, magnetic particles and nanowires, as well as molecular probes and quantum dots. Nanosensors show promise as theranostic tools and as nanoprobes for diagnostic imaging, disease monitoring and the detection of pathogens and environmental contaminants. 

Edited by Prof Ueli Aebi and Prof Peter Gehr.

Adapted from Peña-Bahamonde et. al. 2018 © CC-A 4.0

  1. Macrophage cell membrane-camouflaged nanocarriers can effectively reduce immune cell clearance and actively target tumors. In this study, a macrophage cell membrane-camouflaged mesoporous silica nanorod (MSNR)...

    Authors: Minghua Li, Xiaolong Gao, Chao Lin, Aijun Shen, Jing Luo, Qiongqiong Ji, Jiaqi Wu and Peijun Wang
    Citation: Journal of Nanobiotechnology 2021 19:336
  2. Heavy metal pollution has become more and more serious with industrial development and resource exploitation. Because heavy metal ions are difficult to be biodegraded, they accumulate in the human body and cau...

    Authors: Wenfei Guo, Chuanxiang Zhang, Tingting Ma, Xueying Liu, Zhu Chen, Song Li and Yan Deng
    Citation: Journal of Nanobiotechnology 2021 19:166
  3. A method with high sensitivity, good accuracy and fast response is of ever increasing importance for the simultaneous detection of AA, DA and UA. In this paper, a simple and sensitive electrochemical sensor, w...

    Authors: Yiyong Wu, Peihong Deng, Yaling Tian, Jinxia Feng, Jingyun Xiao, Junhua Li, Jun Liu, Guangli Li and Quanguo He
    Citation: Journal of Nanobiotechnology 2020 18:112
  4. Bacterial biofilms are communities of surface-associated microorganisms living in cellular clusters or micro-colonies, encapsulated in a complex matrix composed of an extracellular polymeric substance, separat...

    Authors: Ella Yeor-Davidi, Marina Zverzhinetsky, Vadim Krivitsky and Fernando Patolsky
    Citation: Journal of Nanobiotechnology 2020 18:81
  5. Nanomedicine is a promising new approach to cancer treatment that avoids the disadvantages of traditional chemotherapy and improves therapeutic indices. However, the lack of a real-time visualization imaging t...

    Authors: Yanlong Jia, Chaochao Wang, Jiehua Zheng, Guisen Lin, Dalong Ni, Zhiwei Shen, Baoxuan Huang, Yan Li, Jitian Guan, Weida Hong, Yuanfeng Chen and Renhua Wu
    Citation: Journal of Nanobiotechnology 2019 17:123
  6. Magnetic nanosensors have become attractive instruments for the diagnosis and treatment of different diseases. They represent an efficient carrier system in drug delivery or in transporting contrast agents. Fo...

    Authors: Simon Doswald, Wendelin Jan Stark and Beatrice Beck-Schimmer
    Citation: Journal of Nanobiotechnology 2019 17:73
  7. Rotavirus is the leading cause of severe dehydrating diarrhea in young children and the inner capsid protein VP6 is a potential vaccine candidate that can induce cross-protective immune responses against diffe...

    Authors: Zhipeng Li, Kuiqing Cui, Hong Wang, Fuhang Liu, Kongwei Huang, Zhaojun Duan, Fengchao Wang, Deshun Shi and Qingyou Liu
    Citation: Journal of Nanobiotechnology 2019 17:13
  8. Tumor-derived exosomes are gaining attention as important factors that facilitate communication between neighboring cells and manipulate cellular processes associated with cancer development or progression. Th...

    Authors: Jiyun Lim, Mihye Choi, HyungJae Lee, Young-Ho Kim, Ji-Youn Han, Eun Sook Lee and Youngnam Cho
    Citation: Journal of Nanobiotechnology 2019 17:1
  9. The need and desire to understand the environment, especially the quality of one’s local water and air, has continued to expand with the emergence of the digital age. The bottleneck in understanding the enviro...

    Authors: Marjorie R. Willner and Peter J. Vikesland
    Citation: Journal of Nanobiotechnology 2018 16:95
  10. Engineered inorganic nanoparticles (NPs) are essential components in the development of nanotechnologies. For applications in nanomedicine, particles need to be functionalized to ensure a good dispersibility i...

    Authors: Muhammad Raisul Abedin, Siddesh Umapathi, Harika Mahendrakar, Tunyaboon Laemthong, Holly Coleman, Denise Muchangi, Santimukul Santra, Manashi Nath and Sutapa Barua
    Citation: Journal of Nanobiotechnology 2018 16:80
  11. Differentiation of telomere length is of vital importance because telomere length is closely related with several deadly diseases such as cancer. Additionally, G-quadruplex and i-motif formation in telomeric D...

    Authors: Shuai Wang, Fei Qu, Wenli Han and Jinmao You
    Citation: Journal of Nanobiotechnology 2018 16:78
  12. Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic ag...

    Authors: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Estefania Vangelie Ramos Campos, Maria del Pilar Rodriguez-Torres, Laura Susana Acosta-Torres, Luis Armando Diaz-Torres, Renato Grillo, Mallappa Kumara Swamy, Shivesh Sharma, Solomon Habtemariam and Han-Seung Shin
    Citation: Journal of Nanobiotechnology 2018 16:71
  13. Due to the high transfer ability of cancer cell, cancer has been regarded as a world-wide high mortality disease. Quantitative analysis of circulating tumor cells (CTCs) can provide some valuable clinical info...

    Authors: Xuan Wu, Tingyu Xiao, Zhang Luo, Rongxiang He, Yiping Cao, Zhenzhong Guo, Weiying Zhang and Yong Chen
    Citation: Journal of Nanobiotechnology 2018 16:65
  14. Chemotherapeutic agents (anti-cancer drugs) are small cytostatic or cytotoxic molecules that often bind to double-stranded DNA (dsDNA) resulting in modifications of their structural and nanomechanical properti...

    Authors: Dennis Kreft, Ying Wang, Michael Rattay, Katja Toensing and Dario Anselmetti
    Citation: Journal of Nanobiotechnology 2018 16:56

    The Correction to this article has been published in Journal of Nanobiotechnology 2019 17:28

  15. As a promising candidate for artificial enzymes, catalytically active nanomaterials show several advantages over natural enzymes, such as controlled synthesis at low cost, tunability of catalytic activities, a...

    Authors: Lin Long, Jianbo Liu, Kaishun Lu, Tao Zhang, Yunqing Xie, Yinglu Ji and Xiaochun Wu
    Citation: Journal of Nanobiotechnology 2018 16:46

    The Correction to this article has been published in Journal of Nanobiotechnology 2019 17:4

  16. Theranostic perfluorocarbon nanoprobes have recently attracted attention due to their fascinating versatility in integrating diagnostics and therapeutics into a single system. Furthermore, although 17β-estradi...

    Authors: Xueli Zhao, Wen Luo, Jing Hu, Lei Zuo, Jing Wang, Rui Hu, Bo Wang, Lei Xu, Jing Li, Meng Wu, Pan Li and Liwen Liu
    Citation: Journal of Nanobiotechnology 2018 16:36