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Impact of comorbidity and multimorbidity on primary care practice

Comorbidity and multimorbidity are often defined as the co-existence of two or more long-term medical conditions. Comorbidity and multimorbidity have been shown to be associated with adverse health outcomes, such as poor quality of life, disability, psychological problems and increased mortality. They also associated with increased frequency of health-service use involving emergency hospital admission, adverse drug events, poly-pharmacy, duplicate testing and poor care co-ordination.

Presently, health care workers have limited guidance or experience as to how to approach care decisions for patients with multimorbidity. Medical training and clinical care has been largely informed by evidence and guidelines for single systems or diseases. Current clinical practice is increasingly specialist, with healthcare professionals often basing treatment decisions on relatively narrow aspects of an individual's health problems. As such our medical care system is particularly ill-prepared to deal with patients with comoribidity and multimorbidity. These issues are especially relevant in certain clinical settings, such as general practice and services caring for the aging population.

In this context, BMC Family Practice presents our special collection focused on the impact of comorbidity and multimoribidty on primary care. This thematic series examines the breadth of research on comorbidity and multimorbidity and their impact on clinical practice in primary care.

Some topics included in the series:
• Comorbid anxiety in patients with long-term conditions (LTCs)
• Access to care for patients with multimorbidity
• Patient perspectives on managing numerous LTCs, including the impact of treatment burden
• Medically unexplained symptoms

For further information, please email in-house editor Tovah Aronin at tovah.aronin@biomedcentral.com 


  1. Content type: Research article

    Multimorbidity is a major issue for primary care. We aimed to explore primary care professionals’ accounts of managing multimorbidity and its impact on clinical decision making and regional health care delivery.

    Authors: Tim Stokes, Emma Tumilty, Fiona Doolan-Noble and Robin Gauld

    Citation: BMC Family Practice 2017 18:51

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  2. Content type: Debate

    Many patients consult their GP because they experience bodily symptoms. In a substantial proportion of cases, the clinical picture does not meet the existing diagnostic criteria for diseases or disorders. This...

    Authors: Marianne Rosendal, Tim C Olde Hartman, Aase Aamland, Henriette van der Horst, Peter Lucassen, Anna Budtz-Lilly and Christopher Burton

    Citation: BMC Family Practice 2017 18:18

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  3. Content type: Research article

    Comorbidity is common in patients consulting in primary care. Musculoskeletal pain and insomnia each increase the risk of the other. Co-occurrence may pose an increased burden on well-being. However, the preva...

    Authors: Shula Baker, John McBeth, Carolyn A. Chew-Graham and Ross Wilkie

    Citation: BMC Family Practice 2017 18:17

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  4. Content type: Research article

    Norwegian general practitioners (GPs) consult on a variety of conditions with a mix of patient types. Patients with chronic diseases benefit from appropriate continuity of care and generally visit their GPs mo...

    Authors: Anastasia Mokienko and Knut Reidar Wangen

    Citation: BMC Family Practice 2016 17:170

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  5. Content type: Research article

    Life and healthcare demand work from patients, more so from patients living with multimorbidity. Patients must respond by mobilizing available abilities and resources, their so-called capacity. We sought to su...

    Authors: Kasey R. Boehmer, Michael R. Gionfriddo, Rene Rodriguez-Gutierrez, Abd Moain Abu Dabrh, Aaron L. Leppin, Ian Hargraves, Carl R. May, Nathan D. Shippee, Ana Castaneda-Guarderas, Claudia Zeballos Palacios, Pavithra Bora, Patricia Erwin and Victor M. Montori

    Citation: BMC Family Practice 2016 17:127

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  6. Content type: Research article

    Multimorbidity poses a major health burden worldwide yet most healthcare is still orientated towards the management of single diseases. Literature on the experience of living with multimorbidity is accumulatin...

    Authors: Peter A. Coventry, Nicola Small, Maria Panagioti, Isabel Adeyemi and Penny Bee

    Citation: BMC Family Practice 2015 16:171

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  7. Content type: Commentary

    Improving the management of people with long-term conditions is a key priority of the UK National Health Service. Whilst the coexistence of two or more long-term conditions in one person is increasingly the no...

    Authors: Valerie Tan, Clare Jinks, Carolyn Chew-Graham, Emma L. Healey and Christian Mallen

    Citation: BMC Family Practice 2015 16:163

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