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MR guided Radiotherapy

MR-guided Radiotherapy © digitalefotografien /

Guest Edited by Dr Stefanie Corradini & Dr Maximilian Niyazi, Ludwig Maximilian University of Munich, Germany.

This special series of Radiation Oncology is dedicated to the latest advancements in Magnetic Resonance (MR)-guided radiotherapy. The recent installation of several MR-linac systems throughout the world marks the beginning of a new era. 

MR is a versatile and suitable imaging modality for image guidance in radiotherapy, as it enables direct soft tissue visualization of the tumor and the surrounding organs at risk. MR-guided radiotherapy can be considered a groundbreaking new technology as it is capable of creating new perspectives towards an individualized, patient-oriented planning and treatment approach. Notably, lesion visibility now enables daily online adaptation strategies and real-time imaging to characterize and eventually track anatomical motion. 

In this special issue of Radiation Oncology dedicated to the latest advancements in MR-guided radiotherapy, a collection of review and research articles highlights the status of the field and discusses recent challenges, but also presents potential future directions.

  1. To assess the effects of daily adaptive MR-guided replanning in stereotactic body radiation therapy (SBRT) of liver metastases based on a patient individual longitudinal dosimetric analysis.

    Authors: Michael Mayinger, Roman Ludwig, Sebastian M. Christ, Riccardo Dal Bello, Alex Ryu, Nienke Weitkamp, Matea Pavic, Helena Garcia Schüler, Lotte Wilke, Matthias Guckenberger, Jan Unkelbach, Stephanie Tanadini-Lang and Nicolaus Andratschke
    Citation: Radiation Oncology 2021 16:84
  2. The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The integration of MRI and PT at the treatmen...

    Authors: Aswin Hoffmann, Bradley Oborn, Maryam Moteabbed, Susu Yan, Thomas Bortfeld, Antje Knopf, Herman Fuchs, Dietmar Georg, Joao Seco, Maria Francesca Spadea, Oliver Jäkel, Christopher Kurz and Katia Parodi
    Citation: Radiation Oncology 2020 15:129
  3. The integration of magnetic resonance imaging (MRI) for guidance in external beam radiotherapy has faced significant research and development efforts in recent years. The current availability of linear acceler...

    Authors: Christopher Kurz, Giulia Buizza, Guillaume Landry, Florian Kamp, Moritz Rabe, Chiara Paganelli, Guido Baroni, Michael Reiner, Paul J. Keall, Cornelis A. T. van den Berg and Marco Riboldi
    Citation: Radiation Oncology 2020 15:93
  4. Magnetic Resonance-guided radiotherapy (MRgRT) marks the beginning of a new era. MR is a versatile and suitable imaging modality for radiotherapy, as it enables direct visualization of the tumor and the surrou...

    Authors: S. Corradini, F. Alongi, N. Andratschke, C. Belka, L. Boldrini, F. Cellini, J. Debus, M. Guckenberger, J. Hörner-Rieber, F. J. Lagerwaard, R. Mazzola, M. A. Palacios, M. E. P. Philippens, C. P. J. Raaijmakers, C. H. J. Terhaard, V. Valentini…
    Citation: Radiation Oncology 2019 14:92
  5. The implementation of magnetic resonance imaging (MRI) guided radiotherapy (RT) continues to increase. Very limited in-vitro data on the interaction of ionizing radiation and magnetic fields (MF) have been pub...

    Authors: B. Yudhistiara, F. Zwicker, K. J. Weber, P. E. Huber, A. Ruehle, S. Brons, P. Haering, J. Debus and S. H. Hauswald
    Citation: Radiation Oncology 2019 14:11