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Molecules of Neural Disorders

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Reviews in this themed series were commissioned by Professors Tim Bliss, Satoshi Kida and Graham Collingridge.
All submissions were handled by Tim Bliss and were independently and externally peer-reviewed.   

  1. Review

    The role of 5-HT receptors in depression

    Depression is a polygenic and highly complex psychiatric disorder that remains a major burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are some of the most commonly...

    Christine N. Yohn, Mark M. Gergues and Benjamin Adam Samuels

    Molecular Brain 2017 10:28

    Published on: 24 June 2017

  2. Review

    Synaptoimmunology - roles in health and disease

    Mounting evidence suggests that the nervous and immune systems are intricately linked. Many proteins first identified in the immune system have since been detected at synapses, playing different roles in norma...

    Robert Nisticò, Eric Salter, Celine Nicolas, Marco Feligioni, Dalila Mango, Zuner A. Bortolotto, Pierre Gressens, Graham L. Collingridge and Stephane Peineau

    Molecular Brain 2017 10:26

    Published on: 20 June 2017

  3. Review

    Propagation of Tau aggregates

    Since 2009, evidence has accumulated to suggest that Tau aggregates form first in a small number of brain cells, from where they propagate to other regions, resulting in neurodegeneration and disease. Propagat...

    Michel Goedert and Maria Grazia Spillantini

    Molecular Brain 2017 10:18

    Published on: 30 May 2017

  4. Review

    Cortical kainate receptors and behavioral anxiety

    The study of glutamatergic synapses mainly focuses on the memory-related hippocampus. Recent studies in the cortical areas such as the anterior cingulate cortex (ACC) show that excitatory synapses can undergo ...

    Min Zhuo

    Molecular Brain 2017 10:16

    Published on: 18 May 2017

  5. Review

    Molecules in pain and sex: a developing story

    Microglia are dynamic immune cells with diverse roles in maintaining homeostasis of the central nervous system. Dysregulation of microglia has been critically implicated in the genesis of neuropathic pain. Per...

    Josiane C. S. Mapplebeck, Simon Beggs and Michael W. Salter

    Molecular Brain 2017 10:9

    Published on: 7 March 2017

  6. Review

    Calcium/calmodulin-dependent kinase II and Alzheimer’s disease

    CaMKII is a remarkably complex protein kinase, known to have a fundamental role in synaptic plasticity and memory formation. Further, CaMKII has also been suggested to be a tau kinase. CaMKII dysregulation may...

    Anshua Ghosh and Karl Peter Giese

    Molecular Brain 2015 8:78

    Published on: 24 November 2015