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Molecules of memory

Series Editors: Tim Bliss, Graham Collingridge

Molecular Brain has published a series of reviews covering the molecular aspects of synaptic plasticity. This series opens with a broad, historical overview by Eric Kandel, followed by a range of reviews from eminent experts in the field

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Series Editors declare no competing interests.

  1. Review

    Fragile X mental retardation protein and synaptic plasticity

    Loss of the translational repressor FMRP causes Fragile X syndrome. In healthy neurons, FMRP modulates the local translation of numerous synaptic proteins. Synthesis of these proteins is required for the maint...

    Michael S Sidorov, Benjamin D Auerbach and Mark F Bear

    Molecular Brain 2013 6:15

    Published on: 8 April 2013

  2. Review

    The CaMKII/NMDAR complex as a molecular memory

    CaMKII is a major synaptic protein that is activated during the induction of long-term potentiation (LTP) by the Ca2+ influx through NMDARs. This activation is required for LTP induction, but the role of the kina...

    Magdalena Sanhueza and John Lisman

    Molecular Brain 2013 6:10

    Published on: 14 February 2013

  3. Review

    Catching the engram: strategies to examine the memory trace

    Memories are stored within neuronal ensembles in the brain. Modern genetic techniques can be used to not only visualize specific neuronal ensembles that encode memories (e.g., fear, craving) but also to select...

    Masanori Sakaguchi and Yasunori Hayashi

    Molecular Brain 2012 5:32

    Published on: 21 September 2012

  4. Review

    Memory maintenance by PKMζ — an evolutionary perspective

    Long-term memory is believed to be maintained by persistent modifications of synaptic transmission within the neural circuits that mediate behavior. Thus, long-term potentiation (LTP) is widely studied as a po...

    Todd Charlton Sacktor

    Molecular Brain 2012 5:31

    Published on: 18 September 2012

  5. Review

    Caspases in synaptic plasticity

    Caspases are a family of cysteine proteases that play key roles in programmed cell death (apoptosis). Mounting evidence in recent years shows that caspases also have important non-apoptotic functions in multip...

    Zheng Li and Morgan Sheng

    Molecular Brain 2012 5:15

    Published on: 14 May 2012