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Call for papers - Musculoskeletal molecular endotypes

Guest Editors:
Ali Mobasheri: University of Oulu, Finland
Guangju Zhai: Memorial University of Newfoundland, Canada

Submission Status: Open   |   Submission Deadline: 30 May 2024
 

BMC Musculoskeletal Disorders announces the launch of a Collection titled, "Musculoskeletal molecular endotypes." This collection explores the growing field of molecular endotypes in musculoskeletal disorders, delving into novel concepts and findings that have the potential to revolutionize and personalize diagnostics, therapies, and patient care.

Recent advances have illuminated the existence of distinct subtypes known as "endotypes" across a range of conditions that affect bones, muscles, tendons, ligaments, and cartilage. This collection explores specific classifications of musculoskeletal disorders based on underlying molecular and cellular characteristics, as well as their implications for stratification in clinical trials, the development of better biomarker tools for studying disease progression, and the development of targeted treatments.

We invite researchers from molecular systems biology, bioinformatics, translational research, exercise physiology, rheumatology, orthopedics, and related disciplines to contribute this collection.

New Content Item This collection supports and amplifies research related to SDG 3: Good Health & Wellbeing.

Meet the Guest Editors

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Ali Mobasheri: University of Oulu, Finland

Dr. Ali Mobasheri is Professor of Musculoskeletal Biology in the Research Unit of Health Sciences and Technology within the Faculty of Medicine at the University of Oulu. He also holds the position of Chief Researcher and International Adviser in the State Research Institute Centre for Innovative Medicine in Vilnius, Lithuania.

He is the Immediate Past President of the Osteoarthritis Research Society International (OARSI) and serves on the Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). In addition, he serves as “Collaborateur Scientifique de l’Université de Liège” and Senior Strategic Advisor to the World Health Organization Collaborating Center for Public Health Aspects of Musculoskeletal Health and Aging, Université de Liège, Liège, Belgium. He is a member of the International Cartilage Regeneration & Joint Preservation Society (ICRS) and serves on the translational science committee of ICRS.

His current research focuses on cartilage biology, specifically cellular metabolism, ion channel physiology and biomarkers of osteoarthritis. He has published more than 350 scientific articles and review articles (358 papers in PubMed, 393 papers in Scopus). His current h-index on Scopus is 70 and he has more than 16,000 citations. He is ranked as one of the top 10 leading experts in the world on “osteoarthritis” and “cartilage” on expertscape.com. Dr. Mobasheri leads a multidisciplinary team of researchers in Vilnius and is building a new team of researchers at the University of Oulu.

Guangju Zhai: Memorial University of Newfoundland, Canada

Dr. Guangju Zhai is a Full Professor at Division of Biomedical Sciences (Genetics), Faculty of Medicine, Memorial University of Newfoundland.

He has over 20 years research experience primarily on osteoarthritis with more than 135 original scientific research publications in major medical journals and has a h-index of 63.

He established the Newfoundland Osteoarthritis Study, which has a primary goal of creating a biobank of human joint tissues and has produced a world-class resource to support multiple osteoarthritis projects and attract national and international collaborators. His research is supported by many funding resources and largely from Canadian Institutes of Health Research (CIHR). His research focuses on biomarker discovery for osteoarthritis and its comorbidities by an OMICS approach. He serves as an Editorial Board Member for BMC Musculoskeletal Disorders.


 

About the Collection

BMC Musculoskeletal Disorders announces the launch of a Collection titled, "Musculoskeletal molecular endotypes." This collection explores the growing field of molecular endotypes in musculoskeletal disorders, delving into novel concepts and findings that have the potential to revolutionize and personalize diagnostics, therapies, and patient care.

Recent advances have illuminated the existence of distinct subtypes known as "endotypes" across a range of conditions that affect bones, muscles, tendons, ligaments, and cartilage. This collection explores specific classifications of musculoskeletal disorders based on underlying molecular and cellular characteristics, as well as their implications for stratification in clinical trials, the development of better biomarker tools for studying disease progression, and the development of targeted treatments.

We invite researchers from molecular systems biology, bioinformatics, translational research, exercise physiology, rheumatology, orthopedics, and related disciplines to contribute this collection, including, but not limited to, research on:

  • Methodologies for categorizing and characterizing distinct molecular endotypes within various musculoskeletal disorders.
  • The molecular pathways, genomic, epigenetic, and metabolic  influences that contribute to the development and modulation of musculoskeletal disorders.
  • Innovative molecular diagnostic tools and biomarkers facilitating early detection, precise classification, and tailored therapeutic approaches for distinct endotypes.
  • Advancements in therapeutic strategies for specific musculoskeletal molecular endotypes, optimizing treatment outcomes and patient well-being.
  • Integration of systems biology, multi-omics technologies, and data-driven/artificial intelligence insights to decipher complex molecular interactions in musculoskeletal disorders.

This collection supports and amplifies research related to SDG 3: Good Health & Wellbeing.

Image credit: ljubaphoto / Getty Images / iStock (Symbolbild mit Fotomodell)

  1. Previous studies have shown that DNA methyltransferase 3b (Dnmt3b) is the only Dnmt responsive to fracture repair and Dnmt3b ablation in Prx1-positive stem cells and chondrocyte cells both delayed fracture rep...

    Authors: Xu Wang, Qinwen Ge, Qinghe Zeng, Kaiao Zou, Zhengsheng Bao, Jun Ying, Zhen Wu, Hongting Jin, Jiali Chen and Taotao Xu
    Citation: BMC Musculoskeletal Disorders 2024 25:180
    Content type: Research Published on:

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Musculoskeletal molecular endotypes" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process  and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.