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miRNA regulation in cancer

Role of miRNA regulation in cancer

Series Editor: Christophe Nicot

This collection of reviews from Molecular Cancer will focus on the important  roles of miRNA in:

  • Shaping the  biology of the Tumor microenvironment (TME)
  • Role of cell-free miRNA in prostate cancer
  • Impact of long noncoding RNAs in cancer
  • Clinical significance of microRNA in Chronic and Acute Human Leukemia

This collection of articles has not been sponsored and articles have undergone the journal's standard peer-review process. Articles have undergone the journal's standard peer-review process overseen by the Editor in Chief.

  1. Review

    Clinical relevance of circulating cell-free microRNAs in ovarian cancer

    Ovarian cancer is the leading cause of death among gynecologic malignancies. Since ovarian cancer develops asymptomatically, it is often diagnosed at an advanced and incurable stage. Despite many years of rese...

    Koji Nakamura, Kenjiro Sawada, Akihiko Yoshimura, Yasuto Kinose, Erika Nakatsuka and Tadashi Kimura

    Molecular Cancer 2016 15:48

    Published on: 24 June 2016

  2. Review

    Diagnostic, prognostic and predictive value of cell-free miRNAs in prostate cancer: a systematic review

    Prostate cancer, the second most frequently diagnosed cancer in males worldwide, is estimated to be diagnosed in 1.1 million men per year. Introduction of PSA testing substantially improved early detection of ...

    Edgars Endzeliņš, Vita Melne, Zane Kalniņa, Vilnis Lietuvietis, Una Riekstiņa, Alicia Llorente and Aija Linē

    Molecular Cancer 2016 15:41

    Published on: 18 May 2016

  3. Review

    Clinical significance of microRNAs in chronic and acute human leukemia

    Small non-coding microRNAs (miRNAs) are epigenetic regulators that target specific cellular mRNA to modulate gene expression patterns and cellular signaling pathways. miRNAs are involved in a wide range of bio...

    Chien-Hung Yeh, Ramona Moles and Christophe Nicot

    Molecular Cancer 2016 15:37

    Published on: 14 May 2016