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Highlights in microRNA

This thematic series, published in Journal of Biomedical Science, highlights recent advances in the research field of microRNA. 

  1. MicroRNAs (miRNAs) are involved in multiple biological activities as well as disease progression including cancer. Interestingly, miRNAs could act as either tumor suppressors or oncogenes depending on the func...

    Authors: Pai-Sheng Chen, Jen-Liang Su and Mien-Chie Hung
    Citation: Journal of Biomedical Science 2012 19:90
  2. Atherosclerosis is commonly appreciated to represent a chronic inflammatory response of the vascular wall, and its complications cause high mortality in patients. Angioplasty with stent replacement is commonly...

    Authors: Li-Jing Chen, Seh Hong Lim, Yi-Ting Yeh, Sheng-Chieh Lien and Jeng-Jiann Chiu
    Citation: Journal of Biomedical Science 2012 19:79
  3. Lipopolysaccharide (LPS) is recognized as the most potent microbial mediator presaging the threat of invasion of Gram-negative bacteria that implicated in the pathogenesis of sepsis and septic shock. This stud...

    Authors: Ching-Hua Hsieh, Cheng-Shyuan Rau, Jonathan Chris Jeng, Yi-Chun Chen, Tsu-Hsiang Lu, Chia-Jung Wu, Yi-Chan Wu, Siou-Ling Tzeng and Johnson Chia-Shen Yang
    Citation: Journal of Biomedical Science 2012 19:69
  4. MiR-1 (microRNA-1) has been used as a positive control in some microRNA experiments. We found that miR-1 transfection of nasopharyngeal carcinoma cells reveals a typical apoptotic process as shown by time-laps...

    Authors: Cheng-Der Wu, Yuan-Sung Kuo, Han-Chung Wu and Chin-Tarng Lin
    Citation: Journal of Biomedical Science 2011 18:80
  5. Autophagy plays a significant role in myocardial ischemia-reperfusion (IR) injury. So it is important to inhibit autophagy to protect cardiomyocytes besides anti-apoptosis. MiRNA has been demonstrated to prote...

    Authors: Jian Xiao, Xiaoyan Zhu, Bin He, Yufeng Zhang, Bo Kang, Zhinong Wang and Xin Ni
    Citation: Journal of Biomedical Science 2011 18:35
  6. Artemin (ARTN) is a neurotrophic factor belonging to the glial cell-derived neurotrophic factor family of ligands. To develop potential therapy targeting ARTN, we studied the roles of miR-223 in the migration ...

    Authors: Shujun Li, Zhigang Li, Fengjie Guo, Xuebo Qin, Bin Liu, Zhe Lei, Zuoqing Song, Liya Sun, Hong-Tao Zhang, Jiacong You and Qinghua Zhou
    Citation: Journal of Biomedical Science 2011 18:24
  7. Ischemic postconditioning (IPost) has aroused much attention since 2003 when it was firstly reported. The role of microRNAs (miRNAs or miRs) in IPost has rarely been reported. The present study was undertaken ...

    Authors: Bin He, Jian Xiao, An-Jing Ren, Yu-Feng Zhang, Hao Zhang, Min Chen, Bing Xie, Xiao-Gang Gao and Ying-Wei Wang
    Citation: Journal of Biomedical Science 2011 18:22
  8. Serum response factor (SRF) regulates certain microRNAs that play a role in cardiac and skeletal muscle development. However, the role of SRF in the regulation of microRNA expression and microRNA biogenesis in...

    Authors: Xiaomin Zhang, Gohar Azhar, Scott A Helms and Jeanne Y Wei
    Citation: Journal of Biomedical Science 2011 18:15