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Highlights in microRNA

This thematic series, published in Journal of Biomedical Science, highlights recent advances in the research field of microRNA. 

  1. Review

    Dysregulation of MicroRNAs in cancer

    MicroRNAs (miRNAs) are involved in multiple biological activities as well as disease progression including cancer. Interestingly, miRNAs could act as either tumor suppressors or oncogenes depending on the func...

    Pai-Sheng Chen, Jen-Liang Su and Mien-Chie Hung

    Journal of Biomedical Science 2012 19:90

    Published on: 17 October 2012

  2. Review

    Roles of microRNAs in atherosclerosis and restenosis

    Atherosclerosis is commonly appreciated to represent a chronic inflammatory response of the vascular wall, and its complications cause high mortality in patients. Angioplasty with stent replacement is commonly...

    Li-Jing Chen, Seh Hong Lim, Yi-Ting Yeh, Sheng-Chieh Lien and Jeng-Jiann Chiu

    Journal of Biomedical Science 2012 19:79

    Published on: 29 August 2012

  3. Research

    Whole blood-derived microRNA signatures in mice exposed to lipopolysaccharides

    Lipopolysaccharide (LPS) is recognized as the most potent microbial mediator presaging the threat of invasion of Gram-negative bacteria that implicated in the pathogenesis of sepsis and septic shock. This stud...

    Ching-Hua Hsieh, Cheng-Shyuan Rau, Jonathan Chris Jeng, Yi-Chun Chen, Tsu-Hsiang Lu, Chia-Jung Wu, Yi-Chan Wu, Siou-Ling Tzeng and Johnson Chia-Shen Yang

    Journal of Biomedical Science 2012 19:69

    Published on: 31 July 2012

  4. Research

    miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma

    Artemin (ARTN) is a neurotrophic factor belonging to the glial cell-derived neurotrophic factor family of ligands. To develop potential therapy targeting ARTN, we studied the roles of miR-223 in the migration ...

    Shujun Li, Zhigang Li, Fengjie Guo, Xuebo Qin, Bin Liu, Zhe Lei, Zuoqing Song, Liya Sun, Hong-Tao Zhang, Jiacong You and Qinghua Zhou

    Journal of Biomedical Science 2011 18:24

    Published on: 31 March 2011

  5. Research

    Role of miR-1 and miR-133a in myocardial ischemic postconditioning

    Ischemic postconditioning (IPost) has aroused much attention since 2003 when it was firstly reported. The role of microRNAs (miRNAs or miRs) in IPost has rarely been reported. The present study was undertaken ...

    Bin He, Jian Xiao, An-Jing Ren, Yu-Feng Zhang, Hao Zhang, Min Chen, Bing Xie, Xiao-Gang Gao and Ying-Wei Wang

    Journal of Biomedical Science 2011 18:22

    Published on: 16 March 2011

  6. Research

    Regulation of cardiac microRNAs by serum response factor

    Serum response factor (SRF) regulates certain microRNAs that play a role in cardiac and skeletal muscle development. However, the role of SRF in the regulation of microRNA expression and microRNA biogenesis in...

    Xiaomin Zhang, Gohar Azhar, Scott A Helms and Jeanne Y Wei

    Journal of Biomedical Science 2011 18:15

    Published on: 8 February 2011