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Molecular genetics and cell biology of eye diseases - Clinical implications

Edited by: Prof Chi Pui Pang

This series was published in Eye and Vision.

  1. Stargardt disease 1 (STGD1; MIM 248200) is a monogenic form of autosomal recessive genetic disease caused by mutation in ABCA4. This gene has a major role in hydrolyzing N-retinylidene-phosphatidylethanolamine to...

    Authors: Rajendran Kadarkarai Raj, Pankaja Dhoble, Rupa Anjanamurthy, Prakash Chermakani, Manojkumar Kumaran, Bharanidharan Devarajan and Periasamy Sundaresan
    Citation: Eye and Vision 2020 7:3
  2. Neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) are sight-threatening maculopathies with both environmental and genetic risk factors. We have previously shown rel...

    Authors: Ke Liu, Li Ma, Timothy Y. Y. Lai, Marten E. Brelen, Pancy O. S. Tam, Clement C. Tham, Chi Pui Pang and Li Jia Chen
    Citation: Eye and Vision 2019 6:34
  3. Fibroblast growth factor 10 (FGF10) is implicated in the growth and development of the eye. Four singles nucleotide polymorphisms (SNPs) in the FGF10 gene (including rs1384449, rs339501, rs12517396 and rs10462070...

    Authors: Lingxi Jiang, Dongyan Luo, Tingting Wang, Rui Zheng, Yaru Zhai, Xiaoqi Liu, Bo Gong, Zhengzheng Wu, Yin Yang, Zhenglin Yang and Yi Shi
    Citation: Eye and Vision 2019 6:33
  4. Loss of cells in the human trabecular meshwork (TM) has been reported with ageing and in glaucoma. This study aims to identify, quantify and determine the age-related changes of human TM stem cells (TMSCs).

    Authors: Yogapriya Sundaresan, Muthukkaruppan Veerappan, Krishnadas Subbiah Ramasamy and Gowri Priya Chidambaranathan
    Citation: Eye and Vision 2019 6:31
  5. Human corneal stromal keratocytes propagated in culture media supplemented with human amnion extract (AME) can correct early corneal haze in an animal model. Clinical application of cultivated keratocytes is l...

    Authors: Beau J. Fenner, Nur Zahirah B. M. Yusoff, Matthias Fuest, Lei Zhou, Francisco Bandeira, Howard Y. Cajucom-Uy, H. K. Tan, Jodhbir S. Mehta and Gary H. F. Yam
    Citation: Eye and Vision 2019 6:30