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Methodology and reporting of diagnostic and prognostic research

A thematic series published in Diagnostic and Prognostic Research.

Edited by:
Gary Collins, University of Oxford, UK
Nancy R Cook, Brigham & Women's Hospital/ Harvard Medical School, USA
Karel GM Moons, University Medical Center Utrecht, Netherlands

To celebrate the launch of Diagnostic and Prognostic Research in 2017, this collection of articles will address different aspects of diagnostic and prognostic research methodology and reporting.

More articles will be added to the collection in due course. If you would like to propose an article for the series to the Editors, please use the contact us email on the journal website.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process outlined in its submission guidelines.

  1. The Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy (DTA) provides guidance on important aspects of conducting a test accuracy systematic review. In this paper we present TOMAS-R (Template...

    Authors: Sue Mallett, Jacqueline Dinnes, Yemisi Takwoingi and Lavinia Ferrante de Ruffano
    Citation: Diagnostic and Prognostic Research 2022 6:18
    Content type: Methodology Published on:

  2. The goal is to investigate prognostic factors for change in memory test performance in healthy older adults and to report and discuss the different statistical procedures used for investigating this topic in t...

    Authors: Mandy Roheger, Ann-Kristin Folkerts, Fabian Krohm, Nicole Skoetz and Elke Kalbe
    Citation: Diagnostic and Prognostic Research 2020 4:7
    Content type: Review Published on:

  3. Most randomized controlled trials evaluating medical interventions have a pre-specified hypothesis, which is statistically tested against the null hypothesis of no effect. In diagnostic accuracy studies, study...

    Authors: Daniël A. Korevaar, Gowri Gopalakrishna, Jérémie F. Cohen and Patrick M. Bossuyt
    Citation: Diagnostic and Prognostic Research 2019 3:22
    Content type: Methodology Published on:

  4. Prognostic markers use an individual’s characteristics at a given time to predict future disease events, with the ultimate goal of guiding medical decision-making. If an accurate prediction can be made, then a...

    Authors: Aasthaa Bansal and Patrick J. Heagerty
    Citation: Diagnostic and Prognostic Research 2019 3:14
    Content type: Methodology Published on:

  5. Over the past few years, evidence synthesis has become essential to investigate and improve the generalizability of medical research findings. This strategy often involves a meta-analysis to formally summarize...

    Authors: Thomas P.A. Debray, Valentijn M.T. de Jong, Karel G.M. Moons and Richard D. Riley
    Citation: Diagnostic and Prognostic Research 2019 3:13
    Content type: Methodology Published on:

  6. Personalized, precision, and risk-based medicine are becoming increasingly important in medicine. These involve the use of information about the prognosis of a patient, to make individualized treatment decisio...

    Authors: Johanna A. A. G. Damen and Lotty Hooft
    Citation: Diagnostic and Prognostic Research 2019 3:2
    Content type: Commentary Published on:

  10. Clinical predictive models (CPMs) estimate the probability of clinical outcomes and hold the potential to improve decision-making and individualize care. The Tufts Predictive Analytics and Comparative Effectiv...

    Authors: Benjamin S. Wessler, Jessica Paulus, Christine M. Lundquist, Muhammad Ajlan, Zuhair Natto, William A. Janes, Nitin Jethmalani, Gowri Raman, Jennifer S. Lutz and David M. Kent
    Citation: Diagnostic and Prognostic Research 2017 1:20
    Content type: Review Published on: