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Innovation and step-change in mechanical ventilation

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Biomedical Engineering Online presents a special collection on “Innovation and step-change in mechanical ventilation”. Mechanical ventilation is one of the single largest reasons for intensive care unit admission, length of stay, mortality, and thus cost. However, the overall method of care has not fundamentally changed in the last 40 years, despite the appearance of new technologies and imaging modalities with the potential to improve care. Covid-19 has further highlighted the need for greater productivity and personalisation in mechanical ventilation (MV) care to meet growing demand, as well as the spikes of demand seen in pandemic. Significantly increasing the personalisation and productivity of MV care will require major inter-disciplinary efforts from clinical medicine, engineering, computational sciences, and physiology / genomics. However, technologically and clinically feasible solutions alone potentially may not suffice, illustrating a role for social sciences to ensure such innovations are adopted. This special section specifically seeks novel, inter-disciplinary approaches to mechanical ventilation, from new ideas with minimal validation, to examination of how innovation is adopted in intensive care medicine and how this understanding can be used to improve translation of innovation to clinical practice, and everything in between.

This collection is now closed to submissions.

Guest Editors: Prof Knut Moeller, Furtwangen University, Germany; Prof Geoffrey Chase,University of Canterbury, New Zealand; Dr Thomas Desaive, University of Liege, Belgium

  1. Patient-specific lung mechanics during mechanical ventilation (MV) can be identified from measured waveforms of fully ventilated, sedated patients. However, asynchrony due to spontaneous breathing (SB) effort ...

    Authors: Cong Zhou, J. Geoffrey Chase, Qianhui Sun, Jennifer Knopp, Merryn H. Tawhai, Thomas Desaive, Knut Möller, Geoffrey M. Shaw, Yeong Shiong Chiew and Balazs Benyo
    Citation: BioMedical Engineering OnLine 2022 21:16
  2. The role of high-frequency oscillatory ventilation (HFOV) has long been debated. Numerous studies documented its benefits, whereas several more recent studies did not prove superiority of HFOV over protective ...

    Authors: Karel Roubík, Jakub Ráfl, Martin Rožánek, Petr Kudrna and Mikuláš Mlček
    Citation: BioMedical Engineering OnLine 2022 21:14
  3. Mechanical ventilation (MV) is the primary form of care for respiratory failure patients. MV settings are based on general clinical guidelines, intuition, and experience. This approach is not patient-specific ...

    Authors: Jay Wing Wai Lee, Yeong Shiong Chiew, Xin Wang, Mohd Basri Mat Nor, J. Geoffrey Chase and Thomas Desaive
    Citation: BioMedical Engineering OnLine 2022 21:13
  4. The study aims at solving the problem with the limitations of the homecare CPAP equipment such as sleep apnea devices in the treatment of COVID-19 pneumonia. By adding an advanced, rapid-to-produce oxygenation...

    Authors: Dmitrijs Bliznuks, Svjatoslavs Kistkins, Jevgēnijs Teličko, Vadims Geža, Ģirts Zāģeris, Artis Svaža, Emil Syundyukov, Mārtiņš Purenkovs, Dana Zeme, Solveiga Jēkabsone, Dace Žentiņa, Valdis Pīrāgs and Immanuels Taivans
    Citation: BioMedical Engineering OnLine 2022 21:10
  5. Systems aiding in selecting the correct settings for mechanical ventilation should visualize patient information at an appropriate level of complexity, so as to reduce information overload and to make reasonin...

    Authors: Stephen Edward Rees, Savino Spadaro, Francesca Dalla Corte, Nilanjan Dey, Jakob Bredal Brohus, Gaetano Scaramuzzo, David Lodahl, Robert Ravnholt Winding, Carlo Alberto Volta and Dan Stieper Karbing
    Citation: BioMedical Engineering OnLine 2022 21:5