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Mitochondria Dysfunctions and Neurodegenerative Diseases

Guest edited by Dr Xiongwei Zhu, Case Western Reserve University School of Medicine

A thematic series published in Translational Neurodegeneration.

iStock-1284442724 © koto_feja / Getty Images / iStock

This series covers updates of mitochondria and pathogenesis of Parkinson’s disease (PD) and other neurodegenerative diseases, mitochondria as therapeutic or modification targets of PD and other neurodegenerative diseases.

  1. Microbiome-gut-brain axis may be involved in the progression of age-related cognitive impairment and relevant brain structure changes, but evidence from large human cohorts is lacking. This study was aimed to ...

    Authors: Xinxiu Liang, Yuanqing Fu, Wen-ting Cao, Zhihong Wang, Ke Zhang, Zengliang Jiang, Xiaofang Jia, Chun-ying Liu, Hong-rou Lin, Haili Zhong, Zelei Miao, Wanglong Gou, Menglei Shuai, Yujing Huang, Shengdi Chen, Bing Zhang…
    Citation: Translational Neurodegeneration 2022 11:49
  2. Neurological disorders (NDs) are characterized by progressive neuronal dysfunction leading to synaptic failure, cognitive impairment, and motor injury. Among these diseases, Alzheimer's disease (AD), Parkinson...

    Authors: Margrethe A. Olesen, Francisca Villavicencio-Tejo and Rodrigo A. Quintanilla
    Citation: Translational Neurodegeneration 2022 11:36
  3. Advancing age is a major risk factor for Alzheimer’s disease (AD). This raises the question of whether AD biology mechanistically diverges from aging biology or alternatively represents exaggerated aging. Corr...

    Authors: Heather M. Wilkins and Russell H. Swerdlow
    Citation: Translational Neurodegeneration 2021 10:33