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Lytic polysaccharide monooxygenases

Lytic polysaccharide monooxygenases (LPMOs) are copper enzymes discovered within the last ten years. By degrading oxidatively recalcitrant substrates, these enzymes are major contributors to the recycling of carbon in nature. This enlarging class of exciting enzymes is of great interest from a mechanistic point of view and for a wide range of biotechnological applications. After the first successful meeting held in Copenhagen in 2016, the second LPMO symposium was organized in Marseille (France) in November 2018.  This special issue in Biotechnology for Biofuels presents top articles from the symposium, contributing to the knowledge of LPMOs on chemistry of catalysis, enzyme diversity, enzymology and industrial applicability for the degradation and modification of polysaccharides.

Guest Editors – Jean-Guy Berrin and Paul Walton

  1. Lytic polysaccharide monooxygenases (LPMOs) are powerful enzymes that oxidatively cleave plant cell wall polysaccharides. LPMOs classified as fungal Auxiliary Activities family 9 (AA9) have been mainly studied...

    Authors: Peicheng Sun, Christophe V. F. P. Laurent, Stefan Scheiblbrandner, Matthias Frommhagen, Dimitrios Kouzounis, Mark G. Sanders, Willem J. H. van Berkel, Roland Ludwig and Mirjam A. Kabel
    Citation: Biotechnology for Biofuels 2020 13:95
  2. The quest for novel enzymes for cellulosic biomass-degradation has recently been focussed on lytic polysaccharide monooxygenases (LPMOs/PMOs), Cu-containing proteins that catalyse the oxidative degradation of ...

    Authors: Claire. A. Fowler, Federico Sabbadin, Luisa Ciano, Glyn R. Hemsworth, Luisa Elias, Neil Bruce, Simon McQueen-Mason, Gideon J. Davies and Paul H. Walton
    Citation: Biotechnology for Biofuels 2019 12:232
  3. Cellulose-active lytic polysaccharide monooxygenases (LPMOs) secreted by filamentous fungi play a key role in the degradation of recalcitrant lignocellulosic biomass. They can occur as multidomain proteins fus...

    Authors: Amani Chalak, Ana Villares, Celine Moreau, Mireille Haon, Sacha Grisel, Angélina d’Orlando, Isabelle Herpoël-Gimbert, Aurore Labourel, Bernard Cathala and Jean-Guy Berrin
    Citation: Biotechnology for Biofuels 2019 12:206
  4. Efforts to develop efficient lignocellulose-degrading enzymatic preparations have led to the relatively recent discovery of a new class of novel cellulase boosters, termed lytic polysaccharide monoxygenases (L...

    Authors: Pooja Dixit, Biswajit Basu, Munish Puri, Deepak Kumar Tuli, Anshu Shankar Mathur and Colin James Barrow
    Citation: Biotechnology for Biofuels 2019 12:185
  5. The increasing interest in replacing petroleum-based products by more sustainable materials in the packaging sector gives relevance to cellulose as a biodegradable natural resource. Moreover, its properties ca...

    Authors: Cristina Valls, F. I. Javier Pastor, M. Blanca Roncero, Teresa Vidal, Pilar Diaz, Josefina Martínez and Susana V. Valenzuela
    Citation: Biotechnology for Biofuels 2019 12:161
  6. Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that cleave polysaccharides through an oxidative mechanism. These enzymes are major contributors to the recycling of carbon in nature an...

    Authors: Céline Moreau, Sandra Tapin-Lingua, Sacha Grisel, Isabelle Gimbert, Sophie Le Gall, Valérie Meyer, Michel Petit-Conil, Jean-Guy Berrin, Bernard Cathala and Ana Villares
    Citation: Biotechnology for Biofuels 2019 12:156
  7. Cyanobacteria have the potential to become next-generation cell factories due to their ability to use CO2, light and inorganic nutrients to produce a range of biomolecules of commercial interest. Synechococcus el...

    Authors: D. A. Russo, J. A. Z. Zedler, D. N. Wittmann, B. Möllers, R. K. Singh, T. S. Batth, B. van Oort, J. V. Olsen, M. J. Bjerrum and P. E. Jensen
    Citation: Biotechnology for Biofuels 2019 12:74
  8. Lytic polysaccharide monooxygenases (LPMOs) are abundant in nature and best known for their role in the enzymatic conversion of recalcitrant polysaccharides such as chitin and cellulose. LPMO activity requires...

    Authors: Vincent G. H. Eijsink, Dejan Petrovic, Zarah Forsberg, Sophanit Mekasha, Åsmund K. Røhr, Anikó Várnai, Bastien Bissaro and Gustav Vaaje-Kolstad
    Citation: Biotechnology for Biofuels 2019 12:58
  9. Lignocellulosic biomass is considered as a promising alternative to fossil resources for the production of fuels, materials and chemicals. Efficient enzymatic systems are needed to degrade the plant cell wall ...

    Authors: Camille Filiatrault-Chastel, David Navarro, Mireille Haon, Sacha Grisel, Isabelle Herpoël-Gimbert, Didier Chevret, Mathieu Fanuel, Bernard Henrissat, Senta Heiss-Blanquet, Antoine Margeot and Jean-Guy Berrin
    Citation: Biotechnology for Biofuels 2019 12:55