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Low Grade Neuroepithelial Neoplasms

The Editors of Acta Neuropathologica Communications invite the submission of articles to a thematic series on low-grade neuroepithelial neoplasms affecting children and young adults.

New Content ItemThe morphologic and molecular heterogeneity exhibited by neuroepithelial tumors likely reflects diversity in terms of both histogenesis and molecular pathogenesis, and has hampered efforts to develop clinically relevant classification schema. Moreover, the association of many of these tumors with intractable epilepsy provides intriguing functional links to brain development. 

This thematic series aims to provide a collection of Reviews and Primary Research Articles that will together present a clearer picture of low-grade neuroepithelial neoplasms, the mechanisms by which they arise, and how they are best approached from the standpoint of clinical neuropathology.

Topics to be covered include (but are not limited to):

  • Case series describing novel pathological entities or disease subgroups
  • Molecular profiling studies
  • Experimental work (in vitro and/or in vivo) on relevant molecular pathways and alterations
  • Developmental neurobiology and its influence on neoplastic processes
  • The impact of the microenvironment on low-grade neuroepithelial neoplasms
  • Classification schema, their development and application

Articles must be submitted through Editorial Manager. All manuscripts received will be subject to peer review as is standard for the journal.

  1. Glioblastoma (GBM) is the most frequent malignant brain tumor, the relapse of which is unavoidable following standard treatment. However, the effective treatment for recurrent GBM is lacking, necessitating the...

    Authors: Xin Wang, Qian Sun, Weiwen Wang, Baohui Liu, Ying Gu and Liang Chen
    Citation: Acta Neuropathologica Communications 2023 11:125
  2. Low grade gliomas are the most frequent brain tumors in children and encompass a spectrum of histologic entities which are currently assigned World Health Organisation grades I and II. They differ substantiall...

    Authors: Scott Ryall, Uri Tabori and Cynthia Hawkins
    Citation: Acta Neuropathologica Communications 2020 8:30