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Lipids as signaling molecules

New Content Item (1)Lipids in Health and Disease invites you to submit to this thematic series. While once viewed as a passive mode of energy storage, lipids are now well-understood to serve as integral components of biological membranes and to function as key intracellular and extracellular messengers. Through this role as signaling molecules, both dietary as well as endogenously synthesized and modified lipids modulate key signaling pathways in the cell.  Aberrant lipid-mediated signaling has been implicated in a variety of pathologies, including metabolic diseases, chronic inflammation, cancer, and Alzheimer’s disease.  The ability of adipose tissue to elaborate a significant number of signaling molecules may lead to its interpretation as an endocrine organ! The lipid molecules for the purpose of this article collection include: saturated and unsaturated fatty acids and their metabolites, sphingolipids and ceramides, endocannabinoids, and other species that are generally regarded as lipids. The collection of papers in this issue addresses the role of lipids as key signaling molecules in health and disease. We would particularly welcome manuscripts that try to bridge the gap between molecular and biochemical aspects of various lipids and their potential clinical applications/implications. 

Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. In the submission system please make sure the correct collection title is chosen from the additional information tab. Please also indicate clearly in the covering letter that the manuscript is to be considered for the "Lipids as signaling molecules" series.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. Non-commissioned submissions will be considered.

You can submit to this series, here.

  1. Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a novel inflammatory marker that has been used to predict various inflammation-related diseases. This study aims to explore the association betwe...

    Authors: Meng-Qi Chen, Wen-Rui Shi, Chu-Ning Shi, Ya-Ping Zhou and Ying-Xian Sun

    Citation: Lipids in Health and Disease 2020 19:48

    Content type: Research

    Published on:

  2. It has been confirmed that the triglyceride to high-density lipoprotein cholesterol ratio (THR) is associated with insulin resistance and metabolic syndrome. However, to the best of our knowledge, only a few s...

    Authors: Xin-Ya Dai, Ying-Ying Zheng, Jun-Nan Tang, Xu-Ming Yang, Qian-Qian Guo, Jian-Chao Zhang, Meng-Die Cheng, Feng-Hua Song, Zhi-Yu Liu, Kai Wang, Li-Zhu Jiang, Lei Fan, Xiao-Ting Yue, Yan Bai, Zeng-Lei Zhang, Ru-Jie Zheng…

    Citation: Lipids in Health and Disease 2019 18:210

    Content type: Research

    Published on: