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Edited by: Prof Jorge Alio, Dr Vishal Jhanji

Keratoconus is a degenerative disorder of the eye which produces a thinning and steepening of the cornea and decreases visual acuity with consequent impact on quality of life. The etiology of keratoconus remains unclear although its pathophysiological mechanisms have been studied for a long time. There is an increasing focus on early detection and treatment on the clinical side in recent years. Research has been done to identify therapeutic strategies that can prevent progression and improve the underlying pathogenesis with long-term efficacy and safety.

This series aim to provide a platform for exchange of innovative ideas and to stimulate high quality research, as well as to disseminate accurate, useful and reliable information and cutting-edge knowledge on the latest developments and new prospects in etiology, diagnosis and treatment of keratoconus. 

This series was published in Eye and Vision

  1. Review

    Tear biomarkers for keratoconus

    Keratoconus is a progressive corneal thinning, ectatic condition, which affects vision. Recent advances in corneal topography measurements has helped advance proper diagnosis of this condition and increased re...

    Krishnatej Nishtala, Natasha Pahuja, Rohit Shetty, Rudy M. M. A. Nuijts and Arkasubhra Ghosh

    Eye and Vision 2016 3:19

    Published on: 4 August 2016

  2. Review

    Genetics in Keratoconus: where are we?

    Keratoconus (KC) is a non-inflammatory thinning and protrusion of the cornea in which the cornea assumes a conical shape. Complex etiology of this condition at present remains an enigma. Although environmental...

    Yelena Bykhovskaya, Benjamin Margines and Yaron S. Rabinowitz

    Eye and Vision 2016 3:16

    Published on: 27 June 2016

  3. Review

    PACK-CXL: Corneal cross-linking in infectious keratitis

    Corneal cross-linking (CXL) using ultraviolet light-A (UV-A) and riboflavin is a technique developed in the 1990’s to treat corneal ectatic disorders such as keratoconus. It soon became the new gold standard i...

    David Tabibian, Cosimo Mazzotta and Farhad Hafezi

    Eye and Vision 2016 3:11

    Published on: 19 April 2016

  4. Review

    The use of intracorneal ring segments in keratoconus

    Keratoconus is a corneal degeneration that usually appears during puberty and may seriously deteriorate the quality of life of the patients. This corneal disease is today the first indication of corneal transp...

    Alfredo Vega-Estrada and Jorge L. Alio

    Eye and Vision 2016 3:8

    Published on: 15 March 2016

  5. Review

    Assessing progression of keratoconus: novel tomographic determinants

    Several methods have been described in the literature to both evaluate and document progression in keratoconus, but there is no consistent or clear definition of ectasia progression. The authors describe how m...

    Joshua K. Duncan, Michael W. Belin and Mark Borgstrom

    Eye and Vision 2016 3:6

    Published on: 11 March 2016

  6. Research

    High intercorneal symmetry in corneal biomechanical metrics

    To evaluate the symmetry of corneal biomechanical metrics, measured using an ocular response analyzer (ORA) and self-built corneal inflation test platform, in bilateral rabbit corneas and to investigate their ...

    XiaoBo Zheng, FangJun Bao, Brendan Geraghty, JinHai Huang, AYong Yu and QinMei Wang

    Eye and Vision 2016 3:7

    Published on: 5 March 2016

  7. Review

    Corneal topography in keratoconus: state of the art

    The morphological characterization of the cornea using corneal topographers is a widespread clinical practice that is essential for the diagnosis of keratoconus. The current state of this non-invasive explorat...

    F. Cavas-Martínez, E. De la Cruz Sánchez, J. Nieto Martínez, F. J. Fernández Cañavate and D. G. Fernández-Pacheco

    Eye and Vision 2016 3:5

    Published on: 22 February 2016