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Lessons Learned from Japanese Association for Cancer Prevention and Future Opportunities

Article collections from Genes and Environment.
Collection published: April 2023

Guest Editor: Futoshi Okada (Tottori University, Japan)

New Content ItemIn commemoration of the 30th anniversary of the establishment of the Japanese Association for Cancer Prevention, Dr. Futoshi Okada (photo) requested Genes and Environment to collect articles on cancer prevention as a joint project with the Japanese Environmental Mutagen and Genome Society. 
As Editor-in-chief, I would like to thank the authors, especially guest editor Dr. Okada, for their contributions. The Articles in this collection focus on recent topics of interest to cancer researchers worldwide. I am sure that many of our readers will find these articles useful in their own research.


  1. Helicobacter pylori secretes cytotoxin-associated gene A (CagA) into the gastric epithelium, causing gastric mucosal atrophy (GMA) and gastric cancer. In contrast, host cells degrade CagA via autophagy. However, ...

    Authors: Naoyuki Yamaguchi, Takuki Sakaguchi, Hajime Isomoto, Tatsuo Inamine, Ryoya Tsukamoto, Daisuke Fukuda, Ken Ohnita, Tsutomu Kanda, Kayoko Matsushima, Tatsuro Hirayama, Kazuo Yashima and Kazuhiro Tsukamoto
    Citation: Genes and Environment 2023 45:18
    Content type: Research Published on:

  2. Exposure to certain chemicals in the environment may contribute to the risk of developing cancer. Although cancer risk from environmental chemical exposure among general populations is considered low compared ...

    Authors: Motoki Iwasaki, Hiroaki Itoh, Norie Sawada and Shoichiro Tsugane
    Citation: Genes and Environment 2023 45:10
    Content type: Review Published on:

  3. Colibactin is a genotoxin produced by Escherichia coli and other Enterobacteriaceae that is believed to increase the risk of colorectal cancer (CRC) of their symbiosis hosts, including human. A peptidase ClbP is ...

    Authors: Tao Zhou, Takayuki Ando, Akihiro Kudo, Michio Sato, Noriyuki Miyoshi, Michihiro Mutoh, Hideki Ishikawa, Keiji Wakabayashi and Kenji Watanabe
    Citation: Genes and Environment 2023 45:8
    Content type: Research Published on:

  4. Cancer is the primary cause of human mortality in Japan since 1981. Although numerous novel therapies have been developed and applied in clinics, the number of deaths from cancer is still increasing worldwide....

    Authors: Shinya Toyokuni, Yingyi Kong, Yashiro Motooka and Shinya Akatsuka
    Citation: Genes and Environment 2023 45:2
    Content type: Review Published on: