Skip to main content


Viruses infecting fish

The International Network on Viruses of Lower Vertebrates (INVLV) wants –first of all– to thank  Veterinary Research, for giving the us the opportunity to prepare this Special Issue exclusively focused on viruses of lower vertebrates.

The INVLV is a network devoted to research on viruses of fish, amphibians and reptiles. The network organizes symposia every 3-4 years to share not only the results of our studies but also  experiences, new ideas and advances in different areas related with the main aim of the Network: the viruses of lower vertebrates.

The reports included in this issue have been selected from a large number of studies reported at the most recent symposium, the 9th International Symposium on Viruses of Lower Vertebrates (ISVLV) held in Málaga in October, 2014. A Committee consisting of 12 specialists belonging to the INVLV and covering different areas of research attended all the sessions and pre-selected 20 studies, based on their general interest, strength of design and experimental tools, and on the recent advances in the field,

After the review of the manuscripts by the panel of experts, we reached the final selection of studies reported here. These papers focus on viruses of different groups, including orthoreoviruses, betanodaviruses, rhabdoviruses, alphaviruses and herpesviruses, and on subjects such as ultrastructures and viral construction, pathogenesis, immunology and biotechnology.
We really hope that these studies will provide interesting and important information for researchers.

Foreword by Prof Alexandra Adams & Prof Carlos P. Dopazo

  1. Research article

    Expression of immunogenic structural proteins of cyprinid herpesvirus 3 in vitro assessed using immunofluorescence

    Cyprinid herpesvirus 3 (CyHV-3), also called koi herpesvirus (KHV), is the aetiological agent of a fatal disease in carp and koi (Cyprinus carpio L.), referred to as koi herpesvirus disease. The virus contains at...

    Sean J. Monaghan, Kim D. Thompson, James E. Bron, Sven M. Bergmann, Tae S. Jung, Takashi Aoki, K. Fiona Muir, Malte Dauber, Sven Reiche, Diana Chee, Shin M. Chong, Jing Chen and Alexandra Adams

    Veterinary Research 2016 47:8

    Published on: 8 January 2016

  2. Research article

    Rainbow trout (Oncorhynchus mykiss) muscle satellite cells are targets of salmonid alphavirus infection

    Sleeping disease in rainbow trout is characterized by an abnormal swimming behaviour of the fish which stay on their side at the bottom of the tanks. This sign is due to extensive necrosis and atrophy of red s...

    Stéphane Biacchesi, Grégory Jouvion, Emilie Mérour, Abdelhak Boukadiri, Marion Desdouits, Simona Ozden, Michel Huerre, Pierre-Emmanuel Ceccaldi and Michel Brémont

    Veterinary Research 2016 47:9

    Published on: 8 January 2016

  3. Research article

    Role of the IFN I system against the VHSV infection in juvenile Senegalese sole (Solea senegalensis)

    Senegalese sole is susceptible to marine VHSV isolates but is not affected by freshwater isolates, which may indicate differences regarding virus-host immune system interaction. IFN I induces an antiviral stat...

    Daniel Alvarez-Torres, Ana M. Podadera, Julia Bejar, Isabel Bandin, M. Carmen Alonso and Esther Garcia-Rosado

    Veterinary Research 2016 47:3

    Published on: 8 January 2016

  4. Research article

    Pathogenesis of experimental salmonid alphavirus infection in vivo: an ultrastructural insight

    Salmonid alphavirus (SAV) is an enveloped, single-stranded, positive sense RNA virus belonging to the family Togaviridae. It causes economically devastating disease in cultured salmonids. The characteristic feat...

    Tharangani K. Herath, Hugh W. Ferguson, Manfred W. Weidmann, James E. Bron, Kimberly D. Thompson, Alexandra Adams, Katherine F. Muir and Randolph H. Richards

    Veterinary Research 2016 47:7

    Published on: 8 January 2016

  5. Research article

    The non-structural protein μNS of piscine orthoreovirus (PRV) forms viral factory-like structures

    Piscine orthoreovirus (PRV) is associated with heart- and skeletal muscle inflammation in farmed Atlantic salmon. The virus is ubiquitous and found in both farmed and wild salmonid fish. It belongs to the family

    Hanne Merethe Haatveit, Ingvild B. Nyman, Turhan Markussen, Øystein Wessel, Maria Krudtaa Dahle and Espen Rimstad

    Veterinary Research 2016 47:5

    Published on: 8 January 2016