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Mobile introns review series

RNA catalysts that are mobile at the DNA level, as are most self-splicing group I and group II introns, are important from mechanistic, evolutionary and biotechnological standpoints. This first Mobile DNA review series  on these elements focuses on their structure, function and evolution. The biotechnological utility of group I and group II Introns, as agents for gene targeting, are covered in the subsequent Mobile genetic elements in biotechnology series.

Edited by: Marlene Belfort, Nancy Craig, Thomas Eickbush, Daniel Voytas

  1. Present in the genomes of bacteria and eukaryotic organelles, group II introns are an ancient class of ribozymes and retroelements that are believed to have been the ancestors of nuclear pre-mRNA introns. Desp...

    Authors: Steven Zimmerly and Cameron Semper
    Citation: Mobile DNA 2015 6:7
  2. Group I introns are intervening sequences that have invaded tRNA, rRNA and protein coding genes in bacteria and their phages. The ability of group I introns to self-splice from their host transcripts, by actin...

    Authors: Georg Hausner, Mohamed Hafez and David R Edgell
    Citation: Mobile DNA 2014 5:8
  3. Group I introns are a distinct class of RNA self-splicing introns with an ancient origin. All known group I introns present in eukaryote nuclei interrupt functional ribosomal RNA genes located in ribosomal DNA...

    Authors: Annica Hedberg and Steinar D Johansen
    Citation: Mobile DNA 2013 4:17