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Constructing 'intelligent' microbial cell factories

New Content Item (1)

This special issue of Microbial Cell Factories covers the topic of 'Constructing 'intelligent' microbial cell factories' by dynamic and systems metabolic engineering approaches.

Edited by Prof Long Liu, Jiangnan University, China

  1. Content type: Research

    Microbial cell factories are widely used in the production of acidic products such as organic acids and amino acids. However, the metabolic activity of microbial cells and their production efficiency are sever...

    Authors: Zhengming Zhu, Jinhua Yang, Peishan Yang, Zhimeng Wu, Juan Zhang and Guocheng Du

    Citation: Microbial Cell Factories 2019 18:136

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  2. Content type: Research

    Heparosan is the unsulfated precursor of heparin and heparan sulfate and its synthesis is typically the first step in the production of bioengineered heparin. In addition to its utility as the starting materia...

    Authors: Asher Williams, Kamil S. Gedeon, Deepika Vaidyanathan, Yanlei Yu, Cynthia H. Collins, Jonathan S. Dordick, Robert J. Linhardt and Mattheos A. G. Koffas

    Citation: Microbial Cell Factories 2019 18:132

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  3. Content type: Research

    Many fermented foods and beverages are produced through the action of complex microbial communities. Synthetic biology approaches offer the ability to genetically engineer these communities to improve the prop...

    Authors: Rachatida Det-udom, Charlie Gilbert, Long Liu, Cheunjit Prakitchaiwattana, Tom Ellis and Rodrigo Ledesma-Amaro

    Citation: Microbial Cell Factories 2019 18:101

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  4. Content type: Review

    Nature has evolved exquisite sensing mechanisms to detect cellular and environmental signals surrounding living organisms. These biosensors have been widely used to sense small molecules, detect environmental ...

    Authors: Xia Wan, Monireh Marsafari and Peng Xu

    Citation: Microbial Cell Factories 2019 18:61

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  5. Content type: Review

    Naturally occurring carotenoids have been isolated and used as colorants, antioxidants, nutrients, etc. in many fields. There is an ever-growing demand for carotenoids production. To comfort this, microbial pr...

    Authors: Chonglong Wang, Shuli Zhao, Xixi Shao, Ji-Bin Park, Seong-Hee Jeong, Hyo-Jin Park, Won-Ju Kwak, Gongyuan Wei and Seon-Won Kim

    Citation: Microbial Cell Factories 2019 18:55

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  6. Content type: RESEARCH

    Streptomyces chattanoogensis L10 is the industrial producer of natamycin and has been proved a highly efficient host for diverse natural products. It has an enormous potential to be developed as a versatile cell ...

    Authors: Qing-Ting Bu, Pin Yu, Jue Wang, Zi-Yue Li, Xin-Ai Chen, Xu-Ming Mao and Yong-Quan Li

    Citation: Microbial Cell Factories 2019 18:16

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  7. Content type: RESEARCH

    The shortage of food based feedstocks has been one of the stumbling blocks in industrial biomanufacturing. The acetone bioproduction from the traditional acetone–butanol–ethanol fermentation is limited by the ...

    Authors: Hao Yang, Bing Huang, Ningyu Lai, Yang Gu, Zhimin Li, Qin Ye and Hui Wu

    Citation: Microbial Cell Factories 2019 18:6

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  8. Content type: RESEARCH

    Glucosamine-6-phosphate N-acetyltransferase (GNA1) is the key enzyme that causes overproduction of N-acetylglucosamine in Bacillus subtilis. Previously, we increased GlcNAc production by promoting the expression ...

    Authors: Wenlong Ma, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du and Long Liu

    Citation: Microbial Cell Factories 2019 18:1

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