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Innate immunity in Alzheimer’s disease

Edited by Donna Wilcock

This review series, published in Alzheimer's Research & Therapy, provides a critical update to the Alzheimer’s field on the state of innate immunity research. Since the last major review of immune mechanisms 12 years ago there has been much progress made in this area. Our goal is to provide a thorough update to the field in a series of review articles.

This series of articles has not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Series Editor, with final decisions made by the Editors-in-Chief. The Series Editor and Editors-in-Chief declare no competing interests.

  1. Inflammatory responses in the brain, which can be demonstrated by changes in properties of microglia, the brain-resident macrophages, are a common feature of human neurodegenerative diseases. Different monocyt...

    Authors: Douglas G. Walker and Lih-Fen Lue
    Citation: Alzheimer's Research & Therapy 2015 7:56
  2. Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting older people worldwide. It is a progressive disorder mainly characterized by the presence of amyloid-beta (Aβ) plaques and neuro...

    Authors: Peter Thériault, Ayman ElAli and Serge Rivest
    Citation: Alzheimer's Research & Therapy 2015 7:41