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Genomics of infection and immunity

Infection and ImmunityGenome Medicine is pleased to present a special issue on Genomics of infection and immunity, co-guest edited by Bali Pulendran and Mark Davis of Stanford School of Medicine. The issue captures recent advances made using genomic approaches toward understanding the function and diversity of the immune system, regulation of the immune response, and the underlying mechanisms of host defense against infection. It also covers pathogen adaptation and evasion strategies, as well as development of tools and approaches to monitor, protect against, and treat infectious disease.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process.

  1. Content type: Method

    Existing methods for paired antibody heavy- and light-chain repertoire sequencing rely on specialized equipment and are limited by their commercial availability and high costs. Here, we report a novel simple a...

    Authors: Praneeth Reddy Devulapally, Jörg Bürger, Thorsten Mielke, Zoltán Konthur, Hans Lehrach, Marie-Laure Yaspo, Jörn Glökler and Hans-Jörg Warnatz

    Citation: Genome Medicine 2018 10:34

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  2. Content type: Method

    B cells play a critical role in the immune response by producing antibodies, which display remarkable diversity. Here we describe a bioinformatic pipeline, BALDR (BCR Assignment of Lineage using De novo Reconstr...

    Authors: Amit A. Upadhyay, Robert C. Kauffman, Amber N. Wolabaugh, Alice Cho, Nirav B. Patel, Samantha M. Reiss, Colin Havenar-Daughton, Reem A. Dawoud, Gregory K. Tharp, Iñaki Sanz, Bali Pulendran, Shane Crotty, F. Eun-Hyung Lee, Jens Wrammert and Steven E. Bosinger

    Citation: Genome Medicine 2018 10:20

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