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Adult immunodeficiency

Hans-Hartmut Peter

  1. Review

    An update on the hyper-IgE syndromes

    The hyper-IgE syndromes (HIES; originally named Job's syndrome) are a collection of primary immunodeficiency syndromes resulting in elevated serum IgE levels and typified by recurrent staphylococcal skin absce...

    Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck and Bodo Grimbacher

    Arthritis Research & Therapy 2012 14:228

    Published on: 30 November 2012

  2. Review

    Common variable immunodeficiency - an update

    Common variable immunodeficiency (CVID) describes a heterogeneous subset of hypogammaglobulinemias of unknown etiology. Typically, patients present with recurrent bacterial infections of the respiratory and ga...

    Ulrich Salzer, Klaus Warnatz and Hans Hartmut Peter

    Arthritis Research & Therapy 2012 14:223

    Published on: 24 September 2012

  3. Review

    Immunoglobulin class-switch recombination deficiencies

    Immunoglobulin class-switch recombination deficiencies (Ig-CSR-Ds) are rare primary immunodeficiencies characterized by defective switched isotype (IgG/IgA/IgE) production. Depending on the molecular defect in...

    Anne Durandy and Sven Kracker

    Arthritis Research & Therapy 2012 14:218

    Published on: 30 July 2012

  4. Review

    Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis

    Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages secreting high amounts of i...

    Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo zur Stadt and Stephan Ehl

    Arthritis Research & Therapy 2012 14:213

    Published on: 8 June 2012