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Adult immunodeficiency

Hans-Hartmut Peter

  1. Content type: Review

    The hyper-IgE syndromes (HIES; originally named Job's syndrome) are a collection of primary immunodeficiency syndromes resulting in elevated serum IgE levels and typified by recurrent staphylococcal skin absce...

    Authors: Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck and Bodo Grimbacher

    Citation: Arthritis Research & Therapy 2012 14:228

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  2. Content type: Review

    Common variable immunodeficiency (CVID) describes a heterogeneous subset of hypogammaglobulinemias of unknown etiology. Typically, patients present with recurrent bacterial infections of the respiratory and ga...

    Authors: Ulrich Salzer, Klaus Warnatz and Hans Hartmut Peter

    Citation: Arthritis Research & Therapy 2012 14:223

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  3. Content type: Review

    Immunoglobulin class-switch recombination deficiencies (Ig-CSR-Ds) are rare primary immunodeficiencies characterized by defective switched isotype (IgG/IgA/IgE) production. Depending on the molecular defect in...

    Authors: Anne Durandy and Sven Kracker

    Citation: Arthritis Research & Therapy 2012 14:218

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  4. Content type: Review

    Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages secreting high amounts of i...

    Authors: Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo zur Stadt and Stephan Ehl

    Citation: Arthritis Research & Therapy 2012 14:213

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