Hans-Hartmut Peter
Adult immunodeficiency
-
Citation: Arthritis Research & Therapy 2013 15:105
-
An update on the hyper-IgE syndromes
The hyper-IgE syndromes (HIES; originally named Job's syndrome) are a collection of primary immunodeficiency syndromes resulting in elevated serum IgE levels and typified by recurrent staphylococcal skin absce...
Citation: Arthritis Research & Therapy 2012 14:228 -
Common variable immunodeficiency - an update
Common variable immunodeficiency (CVID) describes a heterogeneous subset of hypogammaglobulinemias of unknown etiology. Typically, patients present with recurrent bacterial infections of the respiratory and ga...
Citation: Arthritis Research & Therapy 2012 14:223 -
Idiopathic CD4 lymphocytopenia: a case of missing, wandering or ineffective T cells
Idiopathic CD4 lymphocytopenia (ICL) is a presumed heterogenous syndrome with key element low CD4 T-cell counts (below 300/mm3) without evidence of HIV infection or other known immunodeficiency. The etiology, pat...
Citation: Arthritis Research & Therapy 2012 14:222 -
Immunoglobulin class-switch recombination deficiencies
Immunoglobulin class-switch recombination deficiencies (Ig-CSR-Ds) are rare primary immunodeficiencies characterized by defective switched isotype (IgG/IgA/IgE) production. Depending on the molecular defect in...
Citation: Arthritis Research & Therapy 2012 14:218 -
Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy
IL-17 and related cytokines are direct and indirect targets of selective immunosuppressive agents for the treatment of autoimmune diseases and other diseases of pathologic inflammation. Insights into the poten...
Citation: Arthritis Research & Therapy 2012 14:217 -
Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages secreting high amounts of i...
Citation: Arthritis Research & Therapy 2012 14:213