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How I Read Cancer Imaging Studies: The Master Class Series

Surprisingly, in contrast to the literature regarding the outcomes of imaging, the methods that underpin the generation of a report and how to communicate the findings cogently to referring clinicians remains something of a “black box”.

This series of articles appearing in Cancer Imaging showcases experts in various modalities detailing their approach to reporting scans in particular disease settings. We hope that you will be excited to discover this data, which has traditionally been locked into the brains of experts and only intermittently shared with their own direct trainees or alternatively, at often expensive masterclass presentations.
Articles published in the collection have already gone through the systematic peer review process of the journal.

Read the introductory Editorial for ‘How I read cancer imaging studies: the master class series’ written by Prof Rodney Hicks, Editor-in-Chief of Cancer Imaging.


  1. This study was designed to investigate the use of time-dependent diffusion magnetic resonance imaging (MRI) parameters in distinguishing between glioblastomas and brain metastases.

    Authors: Kiyohisa Kamimura, Yoshiki Kamimura, Tsubasa Nakano, Tomohito Hasegawa, Masanori Nakajo, Chihiro Yamada, Kentaro Akune, Fumitaka Ejima, Takuro Ayukawa, Soichiro Ito, Hiroaki Nagano, Koji Takumi, Masatoyo Nakajo, Hiroyuki Uchida, Kazuhiro Tabata, Takashi Iwanaga…
    Citation: Cancer Imaging 2023 23:75
  2. Functional MRI (fMRI) parameters analysis has been proven to be a promising tool of predicting therapeutic response to induction chemotherapy (IC) in nasopharyngeal carcinoma (NPC). The study was designed to iden...

    Authors: Da-wei Zhao, Wen-jun Fan, Ling-ling Meng, Yan-rong Luo, Jian Wei, Kun Liu, Gang Liu, Jin-feng Li, Xiao Zang, Meng Li, Xin-xin Zhang and Lin Ma
    Citation: Cancer Imaging 2021 21:59
  3. Positron Emission Tomography with Computed Tomography (PET/CT) is widely used in the assessment of many diseases, particularly including cancer. However, many factors can affect image quality and diagnostic pe...

    Authors: David Dudoignon, David A. Pattison, Damien Legallois, Rodney J. Hicks and Nicolas Aide
    Citation: Cancer Imaging 2020 20:68
  4. Evaluate the feasibility of fluorine-18 (18F) fluorodeoxyglucose (FDG) positron emission tomography (PET) and magnetic resonance (MR) imaging in patients with gastric cancer by optimizing the scan protocol and to...

    Authors: Dong Zheng, Yi Liu, Jiajin Liu, Ke Li, Mu Lin, Holger Schmidt, Baixuan Xu and Jiahe Tian
    Citation: Cancer Imaging 2020 20:39
  5. Oncological diseases account for a significant portion of the burden on public healthcare systems with associated costs driven primarily by complex and long-lasting therapies. Through the visualization of pati...

    Authors: Thomas Beyer, Luc Bidaut, John Dickson, Marc Kachelriess, Fabian Kiessling, Rainer Leitgeb, Jingfei Ma, Lalith Kumar Shiyam Sundar, Benjamin Theek and Osama Mawlawi
    Citation: Cancer Imaging 2020 20:38
  6. The Vesical Imaging-Reporting and Data System (VI-RADS) was created in 2018, and a 5-point VI-RADS scoring system was proposed to determine whether the muscularis of the bladder has been infiltrated by tumor t...

    Authors: Ziyong Wang, Yunyun Shang, Ting Luan, Yi Duan, Jiansong Wang, Haifeng Wang and Jingang Hao
    Citation: Cancer Imaging 2020 20:26
  7. iRECIST for the objective monitoring of immunotherapies was published by the official RECIST working group in 2017.

    Authors: Thorsten Persigehl, Simon Lennartz and Lawrence H. Schwartz
    Citation: Cancer Imaging 2020 20:2
  8. Technical advances in imaging are well demonstrated by MRI (Magnetic Resonance Imaging) and PET (Positron Emission Tomography). Excellent anatomical detail and a lack of ionising radiation make MRI the standar...

    Authors: Arian Lasocki and Rodney J. Hicks
    Citation: Cancer Imaging 2019 19:57
  9. The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation and reporting of imaging examinations in patients at risk for hepatocellular carcinoma (HCC). For focal liver observations ...

    Authors: Wolfgang Schima and Jay Heiken
    Citation: Cancer Imaging 2018 18:14
  10. PET/CT plays an important role in the diagnosis, staging and management of many pediatric malignancies. The techniques for performing PET/CT examinations in children have evolved, with increasing attention foc...

    Authors: Gabrielle C. Colleran, Neha Kwatra, Leah Oberg, Frederick D. Grant, Laura Drubach, Michael J. Callahan, Robert D. MacDougall, Frederic H. Fahey and Stephan D. Voss
    Citation: Cancer Imaging 2017 17:28
  11. Over the last decade, 18F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT) has gained in popularity for the staging and restaging of patients with prostate cancer (PCa). However, despit...

    Authors: Jean-Mathieu Beauregard and Alexis Beaulieu
    Citation: Cancer Imaging 2016 16:41
  12. 18F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy, restaging following therapy...

    Authors: Michael S. Hofman and Rodney J. Hicks
    Citation: Cancer Imaging 2016 16:35
  13. Liver tumours are fortunately rare in children. Benign tumours such as haemangiomas and cystic mesenchymal hamartomas are typically seen in infancy, often before 6 months of age. After that age, malignant hepa...

    Authors: Susan C. Shelmerdine, Derek J. Roebuck, Alexander J. Towbin and Kieran McHugh
    Citation: Cancer Imaging 2016 16:21
  14. Recently, positron emission tomography (PET) imaging using PSMA-ligands has gained high attention as a promising new radiotracer in patients with prostate cancer (PC). Several studies promise accurate staging ...

    Authors: Isabel Rauscher, Tobias Maurer, Wolfgang P. Fendler, Wieland H. Sommer, Markus Schwaiger and Matthias Eiber
    Citation: Cancer Imaging 2016 16:14
  15. Endometrial cancer is the most common malignancy of the female pelvis. New concepts in endometrial cancer treatment emphasize the value of MRI as a major predictor of lymph node metastasis and tumour recurrenc...

    Authors: Matthias Meissnitzer and Rosemarie Forstner
    Citation: Cancer Imaging 2016 16:11