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Regional hyperthermia as a critical component in the treatment of solid tumors

New Content Item (4)​​​​​​​Guest Edited by Dr Pirus Ghadjar

The aim of this thematic series published in Radiation Oncology is to collect and present the current knowledge of using regional hyperthermia in treatment strategies for solid tumors.



  1. Here we evaluate the current status of clinical research on regional hyperthermia (RHT) in combination with chemotherapy or radiation therapy in paediatric oncology.

    Authors: Georg Seifert, Volker Budach, Ulrich Keilholz, Peter Wust, Angelika Eggert and Pirus Ghadjar
    Citation: Radiation Oncology 2016 11:65
    Content type: Review Published on:

  2. Locoregional hyperthermia combined with radiotherapy significantly improves locoregional control and overall survival for cervical tumors compared to radiotherapy alone. In this study biological modelling is a...

    Authors: J. Crezee, C. M. van Leeuwen, A. L. Oei, L. E. van Heerden, A. Bel, L. J. A. Stalpers, P. Ghadjar, N. A. P. Franken and H. P. Kok
    Citation: Radiation Oncology 2016 11:14
    Content type: Research Published on:

  3. Glioblastoma multiforme is the most common and most aggressive malign brain tumor. The 5-year survival rate after tumor resection and adjuvant chemoradiation is only 10 %, with almost all recurrences occurring...

    Authors: Lukas Winter, Celal Oezerdem, Werner Hoffmann, Tessa van de Lindt, Joao Periquito, Yiyi Ji, Pirus Ghadjar, Volker Budach, Peter Wust and Thoralf Niendorf
    Citation: Radiation Oncology 2015 10:201
    Content type: Research Published on:

  5. The currently available arsenal of anticancer modalities includes many DNA damaging agents that can kill malignant cells. However, efficient DNA repair mechanisms protect both healthy and cancer cells against ...

    Authors: Arlene L. Oei, Lianne E. M. Vriend, Johannes Crezee, Nicolaas A. P. Franken and Przemek M. Krawczyk
    Citation: Radiation Oncology 2015 10:165
    Content type: Research Published on:

  6. Peritoneal carcinomatosis occurs in different cancer subtypes and is associated with a dismal prognosis. Some doubts remain whether the whole abdomen can be treated by regional hyperthermia, therefore we analy...

    Authors: Marcus Beck, Pirus Ghadjar, Mirko Weihrauch, Susen Burock, Volker Budach, Jacek Nadobny, Jalid Sehouli and Peter Wust
    Citation: Radiation Oncology 2015 10:157
    Content type: Research Published on:

  7. Current studies on salvage radiotherapy (sRT) investigate timing, dose-escalation and anti-hormonal treatment (ADT) for recurrent prostate cancer. These approaches could either be limited by radiation-related ...

    Authors: Arndt-Christian Müller, Daniel Zips, Vanessa Heinrich, Ulf Lamprecht, Otilia Voigt, Susen Burock, Volker Budach, Peter Wust and Pirus Ghadjar
    Citation: Radiation Oncology 2015 10:138
    Content type: Study protocol Published on: