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Human evolutionary genomics

Recent biotechnological and bioinformatic advances that enable us to read and analyse genomes of modern and even archaic humans already have led to fascinating insights into human evolution. Analyses of modern and ancient human genomes allow comprehensive investigations into where and when our ancestors originated and migrated, as well as how environmental factors impacted adaptation. With this new series we aim to pay tribute to a new branch of investigative genetics by providing a platform for the rapidly emerging field of human evolutionary genomics. Please submit your manuscript through the website and indicate in your covering letter that you would like it to be considered for the series, or send a pre-submission enquiry to

Prof Manfred Kayser

  1. Detecting and quantifying the population substructure present in a sample of individuals are of main interest in the fields of genetic epidemiology, population genetics, and forensics among others. To date, se...

    Authors: Andreas Wollstein and Oscar Lao
    Citation: Investigative Genetics 2015 6:7
  2. Adaptation can be described as an evolutionary process that leads to an adjustment of the phenotypes of a population to their environment. In the classical view, new mutations can introduce novel phenotypic fe...

    Authors: Andreas Wollstein and Wolfgang Stephan
    Citation: Investigative Genetics 2015 6:5
  3. For a long time, the analysis of ancient human DNA represented one of the most controversial disciplines in an already controversial field of research. Scepticism in this field was only matched by the long-las...

    Authors: Michael Knapp, Carles Lalueza-Fox and Michael Hofreiter
    Citation: Investigative Genetics 2015 6:4
  4. The peopling of Europe and the nature of the Neolithic agricultural migration as a primary issue in the modern human colonization of the globe is still widely debated. At present, much uncertainty is associate...

    Authors: Anahit Hovhannisyan, Zaruhi Khachatryan, Marc Haber, Peter Hrechdakian, Tatiana Karafet, Pierre Zalloua and Levon Yepiskoposyan
    Citation: Investigative Genetics 2014 5:15
  5. Comparisons of maternally-inherited mitochondrial DNA (mtDNA) and paternally-inherited non-recombining Y chromosome (NRY) variation have provided important insights into the impact of sex-biased processes (suc...

    Authors: Sebastian Lippold, Hongyang Xu, Albert Ko, Mingkun Li, Gabriel Renaud, Anne Butthof, Roland Schröder and Mark Stoneking
    Citation: Investigative Genetics 2014 5:13