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Hope of progress

The hope of progress' is the title of a book of essays [1] by Peter Medawar, who believed in the contribution of science to human society, and won the Nobel Prize in 1960, with Frank McFarlane Burnet, for fundamental contributions to immunology. We have adopted it as the title for a series of reviews on the contributions of basic biological research to clinical problems, from the quest for new drugs and new drug targets, to new approaches to the understanding of complex disease. 1. Medawar PB: The Hope of Progress 1972, Methuen, London.

  1. Review

    Assessing the human immune system through blood transcriptomics

    Blood is the pipeline of the immune system. Assessing changes in transcript abundance in blood on a genome-wide scale affords a comprehensive view of the status of the immune system in health and disease. This...

    Damien Chaussabel, Virginia Pascual and Jacques Banchereau

    BMC Biology 2010 8:84

    Published on: 1 July 2010

  2. Review

    Biology-driven cancer drug development: back to the future

    Most of the significant recent advances in cancer treatment have been based on the great strides that have been made in our understanding of the underlying biology of the disease. Nevertheless, the exploitatio...

    Christopher J Lord and Alan Ashworth

    BMC Biology 2010 8:38

    Published on: 12 April 2010

  3. Review

    Immune mechanisms of protection: can adjuvants rise to the challenge?

    For many diseases vaccines are lacking or only partly effective. Research on protective immunity and adjuvants that generate vigorous immune responses may help generate effective vaccines against such pathogens.

    Amy S McKee, Megan KL MacLeod, John W Kappler and Philippa Marrack

    BMC Biology 2010 8:37

    Published on: 12 April 2010