Dr Dawang Zhou
Diversity in function and regulation of the Hippo pathway
Citation:
Cell & Bioscience
2013
3:34
Hippo signaling pathway
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Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators
YAP and TAZ are transcription coactivators and effectors of the Hippo pathway, which play a key role in organ size control. Through interaction with transcription factors such as TEADs, they activate gene tran...
Citation: Cell & Bioscience 2013 3:33 -
Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling
The metazoan Hippo pathway is an essential tumour suppressor signalling cascade that ensures normal tissue growth by co-ordinating cell proliferation, cell death and cell differentiation. Over the past years, ...
Citation: Cell & Bioscience 2013 3:32 -
Mst1 and Mst2 kinases: regulations and diseases
The Hippo signaling pathway has emerged as a critical regulator for organ size control. The serine/threonine protein kinases Mst1 and Mst2, mammalian homologs of the Hippo kinase from Drosophila, play the cent...
Citation: Cell & Bioscience 2013 3:31