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Hereditary angioedema - management consensus 2010

A thematic series published in Allergy, Asthma & Clinical Immunology

This series is meant to review the current international consensus approach for the diagnosis, therapy, and management of hereditary angioedema. The Toronto Consensus meeting was sponsored by the Canadian Hereditary Angioedema Network, the Canadian Society of Allergy and Clinical Immunology and the University of Calgary and supported through an unrestricted educational grant from CSL Behring. The contributed manuscripts and publication of the Consensus were supported by the Canadian Hereditary Angioedema Network and various author university affiliations.

View all article collections published in Allergy, Asthma & Clinical Immunology

  1. Content type: Review

    We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angio...

    Authors: Tom Bowen, Marco Cicardi, Henriette Farkas, Konrad Bork, Hilary J Longhurst, Bruce Zuraw, Emel Aygoeren-Pürsün, Timothy Craig, Karen Binkley, Jacques Hebert, Bruce Ritchie, Laurence Bouillet, Stephen Betschel, Della Cogar, John Dean, Ramachand Devaraj…

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:24

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  2. Content type: Review

    Advances in understanding the pathophysiology and mechanism of swelling in hereditary angioedema (HAE) has resulted in the development of multiple new drugs for the acute and prophylactic treatment of patients...

    Authors: Bruce L Zuraw

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:23

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  3. Content type: Review

    Hereditary angioedema (C1 inhibitor deficiency, HAE) is associated with intermittent swellings which are disabling and may be fatal. Effective treatments are available and these are most useful when given earl...

    Authors: Hilary J Longhurst, Henriette Farkas, Timothy Craig, Emel Aygören-Pürsün, Claire Bethune, Janne Bjorkander, Konrad Bork, Laurence Bouillet, Henrik Boysen, Anette Bygum, Teresa Caballero, Marco Cicardi, John Dempster, Mark Gompels, Jimmy Gooi, Sofia Grigoriadou…

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:22

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  4. Content type: Research

    Manifestation of acute edema in hereditary angioedema (HAE) is characterized by interindividual and intraindividual variability in symptom expression over time. Flexible therapy options are needed.

    Authors: Emel Aygören-Pürsün, Inmaculada Martinez-Saguer, Eva Rusicke, Thomas Klingebiel and Wolfhart Kreuz

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:21

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  5. Content type: Research

    C1-inhibitor (C1-INH) deficiency is a rare blood disorder resulting in angioedema attacks that are debilitating and may be life-threatening. Prophylaxis and therapy of events has changed since our first Canadi...

    Authors: Tom Bowen, John Brosz, Kristylea Brosz, Jacques Hebert and Bruce Ritchie

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:20

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  6. Content type: Review

    Women with hereditary angioedema (HAE) are more likely to be symptomatic that men. Hormonal factors (puberty, contraception, pregnancy,....) play a significant role in the precipitation or worsening of the con...

    Authors: Laurence Bouillet

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:17

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  7. Content type: Review

    Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released ...

    Authors: Marco Cicardi and Andrea Zanichelli

    Citation: Allergy, Asthma & Clinical Immunology 2010 6:14

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