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Interaction of Helicobacter pylori with its host cell

Edited by Silja Wessler

The current knowledge of H. pylori pathogenesis is incomplete, but already points to a strictly regulated multi-step process. This special issue in Cell Communication and Signaling provides a comprehensive overview of presently known H. pylori-activated signal transduction pathways leading to different cellular processes and emphasizes the complexity of the communication between H. pylori and its host.

View all collections published in Cell Communication and Signaling

  1. Helicobacter pylori is a highly successful pathogen uniquely adapted to colonize humans. Gastric infections with this bacterium can induce pathology ranging from chronic gastritis and peptic ulcers to gastric can...

    Authors: Steffen Backert, Marguerite Clyne and Nicole Tegtmeyer
    Citation: Cell Communication and Signaling 2011 9:28
  2. Dynamic rearrangement of the actin cytoskeleton is a significant hallmark of Helicobacter pylori (H. pylori) infected gastric epithelial cells leading to cell migration and invasive growth. Considering the cellul...

    Authors: Silja Wessler, Mario Gimona and Gabriele Rieder
    Citation: Cell Communication and Signaling 2011 9:27
  3. VacA, the vacuolating cytotoxin A of Helicobacter pylori, induces apoptosis in epithelial cells of the gastic mucosa and in leukocytes. VacA is released by the bacteria as a protein of 88 kDa. At the outer surfac...

    Authors: Joachim Rassow
    Citation: Cell Communication and Signaling 2011 9:26
  4. Persistent infection with the gastric bacterial pathogen Helicobacter pylori causes gastritis and predisposes carriers to a high gastric cancer risk, but has also been linked to protection from allergic, chronic ...

    Authors: Anne M├╝ller, Mathias Oertli and Isabelle C Arnold
    Citation: Cell Communication and Signaling 2011 9:25