Skip to main content


Interaction of Helicobacter pylori with its host cell

Edited by Silja Wessler

The current knowledge of H. pylori pathogenesis is incomplete, but already points to a strictly regulated multi-step process. This special issue in Cell Communication and Signaling provides a comprehensive overview of presently known H. pylori-activated signal transduction pathways leading to different cellular processes and emphasizes the complexity of the communication between H. pylori and its host.

View all collections published in Cell Communication and Signaling

  1. Review

    "Targeted disruption of the epithelial-barrier by Helicobacter pylori"

    Helicobacter pylori colonizes the human gastric epithelium and induces chronic gastritis, which can lead to gastric cancer. Through cell-cell contacts the gastric epithelium forms a barrier to protect underlying ...

    Lydia E Wroblewski and Richard M Peek Jr

    Cell Communication and Signaling 2011 9:29

    Published on: 1 November 2011

  2. Review

    Helicobacter pylori vacuolating toxin A and apoptosis

    VacA, the vacuolating cytotoxin A of Helicobacter pylori, induces apoptosis in epithelial cells of the gastic mucosa and in leukocytes. VacA is released by the bacteria as a protein of 88 kDa. At the outer surfac...

    Joachim Rassow

    Cell Communication and Signaling 2011 9:26

    Published on: 1 November 2011