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Call for papers: Health outcomes, values and guidelines – expanding the scope of HQLO

Current special series and section editors: Dr Jan Brozek, Dr Yaolong Chen, Dr Pablo Alonso Coello, Dr Joerg J Meerpohl, Dr Yuan Zhang, Prof Holger Schünemann of Health and Quality of Life Outcomes invite you to submit to our special series and section: Health outcomes, values and guidelines.

Improving health outcomes is the ultimate goal of recommendations made in health guidelines and other guidance statements. People important outcomes (PIOs), including the relative importance of these outcomes, quality of life assessment, values and preferences and best methods for integrating them in health care guidelines are at the forefront of methodological and clinical practice research. Considering PIOs in the context of other criteria that influence a health care decision to achieve the greatest possible desirable consequences of a health care option is a preeminent goal of a guideline recommendation. The improvement of both the development of guideline recommendations through methodological research and practical application will now be considered for publication in Health and Quality of Life Outcomes, beginning with a special series.

Health and Quality of Life Outcomes will, for this special series, and subsequent issues consider the following articles for publication on guidelines and guideline methodology: clinical, public health and other health related recommendations and guidelines/guidance, including supplementary materials for guidelines, such as Evidence to Decision Frameworks; and, scientific articles describing methodological research and standards to improve the development, dissemination and implementation of guidelines. For future issues of the journal we do also invite editorials and opinion pieces about guideline development.

Submitted guidelines should follow standards set by the Institutes of Medicine and the Guideline International Network and utilize appropriate methods for the development of guidelines such as the GIN-McMaster Guideline Development checklist. These standards include the use of proven approaches to assess the certainty in the evidence and move from evidence to decisions such as the GRADE approach. Authors of guidelines should follow the RIGHT statement (reference to EQUATOR) for reporting of guidelines to achieve high scores on assessment instruments such as the AGREE instrument.

Manuscripts should be formatted according to Health and Quality of Life Outcomes submission guidelines and submitted via the online submission system. All articles in this series will undergo the journal’s full standard peer-review process. In the submission system please make sure the correct collection title is chosen from the “additional information” tab. Please also indicate in the covering letter that the manuscript is to be considered for the ‘Guidelines and guideline methodology’ special series. For further information, please contact the Editors (hqlo@biomedcentral.com).


  1. Content type: Review

    Low health literacy often has an association with poor health outcomes such as low levels of self-efficacy, increased mortality, poor health status and reduced quality of life (QOL). The aim of the study was t...

    Authors: Mengyun Zheng, Hui Jin, Naiyang Shi, Chunxiao Duan, Donglei Wang, Xiaoge Yu and Xiaoning Li

    Citation: Health and Quality of Life Outcomes 2018 16:201

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  2. Content type: Research

    The Pain Disability Index (PDI) is a widely-used instrument to measure pain-related disability. The aim of this study was to assess the responsiveness and interpretation of change score of the PDI in patients ...

    Authors: T. Beemster, C. van Bennekom, J. van Velzen, M. Reneman and M. Frings-Dresen

    Citation: Health and Quality of Life Outcomes 2018 16:182

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  3. Content type: Research

    Generic assessments are less responsive to subtle changes due to specific diseases, making it challenging to fully understand the impact of pulmonary tuberculosis (TB) on patient’s quality of life (QOL).

    Authors: Yanchun Sun, Zheng Yang, Chonghua Wan, Chuanzhi Xu, Liuping Chen, Lin Xu, Xiaoqing Zhang and Fei Yan

    Citation: Health and Quality of Life Outcomes 2018 16:137

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  4. Content type: Research

    Despite the high prevalence of lymphedema in Iranian breast cancer patients, there is no valid instrument for measuring quality of life in this population. The aim of this study was to assess reliability and v...

    Authors: Shahpar Haghighat, Ali Montazeri, Farid Zayeri, Mandana Ebrahimi and Jan Weiss

    Citation: Health and Quality of Life Outcomes 2018 16:132

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  5. Content type: Research

    Young adult patients with cancer have to deal with their disease in an eventful phase of life. A common side effect of cancer and its treatment is cancer-related fatigue (CRF), a phenomenon which can thwart su...

    Authors: Michael Friedrich, Erik Nowe, Dirk Hofmeister, Susanne Kuhnt, Katja Leuteritz, Annekathrin Sender, Yve Stöbel-Richter and Kristina Geue

    Citation: Health and Quality of Life Outcomes 2018 16:125

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  6. Content type: Research

    International reports indicating that around 10–50% of health care staff are exposed to violence every year; in certain settings, this rate might reach over 85%. Evidence has shown that people who experience p...

    Authors: Peng Li, Kai Xing, Hong Qiao, Huiying Fang, Hongkun Ma, Mingli Jiao, Yanhua Hao, Ye Li, Libo Liang, Lijun Gao, Zheng Kang, Yu Cui, Hong Sun, Qunhong Wu and Ming Liu

    Citation: Health and Quality of Life Outcomes 2018 16:117

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  7. Content type: Research

    Quality of life can be used to measure the effect of intervention on health related conditions. Health insurance contributes positive effect on availability of medical supplies and empowerment of women and chi...

    Authors: Teklemichael Gebru and Kifle Lentiro

    Citation: Health and Quality of Life Outcomes 2018 16:110

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  8. Content type: Research

    In China, the problems of population aging and empty nesting have become important issues which will affect the social stability and economic development. The aim of this study was to explore the health promot...

    Authors: Chichen Zhang, Ruifang Zhu, Jiao Lu, Yaqing Xue, Lihong Hou, Mimi Li, Xiao Zheng, Tingzhong Yang and Jianzhong Zheng

    Citation: Health and Quality of Life Outcomes 2018 16:103

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  9. Content type: Research

    There are various instruments and methods to evaluate spinal health and functional status. Whole-spine patient reported outcome (PRO) measures, such as the Spine Functional Index (SFI), assess the spine from t...

    Authors: Hamid Reza Mokhtarinia, Azadeh Hosseini, Azam Maleki-Ghahfarokhi, Charles Philip Gabel and Majid Zohrabi

    Citation: Health and Quality of Life Outcomes 2018 16:95

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  10. Content type: Review

    The Pittsburgh Sleep Quality Index (PSQI) dimensionality is much debated, with the greatest number of reported factor structures. Therefore, this review appraised the methodologies of studies investigating the...

    Authors: Md Dilshad Manzar, Ahmed S. BaHammam, Unaise Abdul Hameed, David Warren Spence, Seithikurippu R. Pandi-Perumal, Adam Moscovitch and David L. Streiner

    Citation: Health and Quality of Life Outcomes 2018 16:89

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  11. Content type: Research

    Infertility can cause psychological distress and has a negative impact on quality of life (QoL). There have been no studies investigating the effect of depression on QoL in infertile couples at the dyadic leve...

    Authors: Saman Maroufizadeh, Mostafa Hosseini, Abbas Rahimi Foroushani, Reza Omani-Samani and Payam Amini

    Citation: Health and Quality of Life Outcomes 2018 16:73

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  12. Content type: Research

    With the elderly population comprising an increasing large proportion of society, a valid and reliable measure of social health in the elderly is indispensable for a comprehensive health assessment. The object...

    Authors: Chengzhen Bao, Zhebin Yu, Xuefen Yin, Zhen Chen, Lu Meng, Weibo Yang, Xueyu Chen, Mingjuan Jin, Jianbing Wang, Mengling Tang and Kun Chen

    Citation: Health and Quality of Life Outcomes 2018 16:67

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  13. Content type: Research

    In Ethiopia assuring the satisfaction of health care provider with their job is a major challenging problem. Job satisfaction is a worker’s emotional response to different job related factors resulting in find...

    Authors: Kalkidan Temesgen, Moges Wubie Aycheh and Cheru Tesema Leshargie

    Citation: Health and Quality of Life Outcomes 2018 16:65

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  14. Content type: Research

    To assess the influence of combined training on pain, fatigue, maximal oxygen uptake (VO2 max), body mass index (BMI), flexibility, and strength in patients with breast cancer.

    Authors: Andréa Dias Reis, Paula Tamara Vieira Teixeira Pereira, Renata Rodrigues Diniz, Jurema Gonçalves Lopes de Castro Filha, Alcione Miranda dos Santos, Bianca Trovello Ramallo, Florentino Assenço Alves Filho, Francisco Navarro and João Batista Santos Garcia

    Citation: Health and Quality of Life Outcomes 2018 16:58

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  15. Content type: Review

    Patients with prostate cancer (PC) may be ready to make trade-offs between their quantity and their quality of life. For instance, elderly patients may prefer the absence of treatment if it is associated with ...

    Authors: Yohann Foucher, Marine Lorent, Philippe Tessier, Stéphane Supiot, Véronique Sébille and Etienne Dantan

    Citation: Health and Quality of Life Outcomes 2018 16:40

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  16. Content type: Research

    Several diseases may lead to the need for liver transplantation due to progressive organ damage until the onset of cirrhosis, resulting in changes in interpersonal relationships. Social Support for transplant ...

    Authors: Clerison Stelvio Garcia, Agnaldo Soares Lima, Ehideé Isabel Gómez La-Rotta and Ilka de Fátima Santana Ferreira Boin

    Citation: Health and Quality of Life Outcomes 2018 16:35

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  17. Content type: Research

    To evaluate and analyse the factors associated with health-related quality of life (HR-QoL) in the Korean population aged 50 years and older.

    Authors: Kyoung Min Kwon, Jung Soo Lee, Na Eun Jeon and Yeo Hyung Kim

    Citation: Health and Quality of Life Outcomes 2017 15:243

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  18. Content type: Research

    Quality of life must be one of the main purposes for the treatment of drug users, requiring a better understanding of the association between the quality of life and the severity of dependency. This study aime...

    Authors: Selva Rios Campêlo, Maria Alves Barbosa, Danilo Rocha Dias, Camila Cardoso Caixeta, Cláudio Rodrigues Leles and Celmo Celeno Porto

    Citation: Health and Quality of Life Outcomes 2017 15:223

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  19. Content type: Research

    Women treated for breast cancer are followed-up for monitoring of treatment effectiveness and for detecting recurrences at an early stage. The type of follow-up received may affect women’s reassurance and impa...

    Authors: Alessandra Lafranconi, Liisa Pylkkänen, Silvia Deandrea, Anke Bramesfeld, Donata Lerda, Luciana Neamțiu, Zuleika Saz-Parkinson, Margarita Posso, David Rigau, Ivan Sola, Pablo Alonso-Coello and Maria José Martinez-Zapata

    Citation: Health and Quality of Life Outcomes 2017 15:206

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  20. Content type: Research

    It has been hypothesized that adaptation of health practice guidelines to the local setting is expected to improve their uptake and implementation while cutting on required resources. We recently adapted the p...

    Authors: Andrea Darzi, Manale Harfouche, Thurayya Arayssi, Samar Alemadi, Khalid A. Alnaqbi, Humeira Badsha, Farida Al Balushi, Bassel Elzorkany, Hussein Halabi, Mohammed Hamoudeh, Wissam Hazer, Basel Masri, Mohammed A. Omair, Imad Uthman, Nelly Ziade, Jasvinder A. Singh…

    Citation: Health and Quality of Life Outcomes 2017 15:183

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    The Correction to this article has been published in Health and Quality of Life Outcomes 2017 15:214

  21. Content type: Short report

    Shoulder pain is a common musculoskeletal disorder in Chinese population, which affects more than 1,3 billion individuals. To the best of our knowledge, there has been no available Chinese-language version of ...

    Authors: Min Yao, Long Yang, Zuo-yuan Cao, Shao-dan Cheng, Shuang-lin Tian, Yue-li Sun, Jing Wang, Bao-ping Xu, Xiao-chun Hu, Yong-jun Wang, Ying Zhang and Xue-jun Cui

    Citation: Health and Quality of Life Outcomes 2017 15:178

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  22. Content type: Research

    The Center for Epidemiological Studies Depression Scale (CES-D) is an instrument that is commonly used to screen for depression in patients with chronic disease, but the characteristics of the CES-D in adults ...

    Authors: Ju Ryoung Moon, June Huh, Jinyoung Song, I-Seok Kang, Seung Woo Park, Sung-A Chang, Ji-Hyuk Yang and Tae-Gook Jun

    Citation: Health and Quality of Life Outcomes 2017 15:176

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  23. Content type: Research

    Health-related quality of life (HRQoL) is an important outcome measure among HIV infected patients receiving antiretroviral therapy (ART). When HIV infected patients coinfected with Visceral Leishmaniasis (VL)...

    Authors: Mekuriaw Alemayehu, Mamo Wubshet, Nebiyu Mesfin, Aschalew Tamiru and Abebaw Gebayehu

    Citation: Health and Quality of Life Outcomes 2017 15:65

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  24. Content type: Research

    Identifying scientific literature addressing patients’ views and preferences is complex due to the wide range of studies that can be informative and the poor indexing of this evidence. Given the lack of guidan...

    Authors: Anna Selva, Ivan Solà, Yuan Zhang, Hector Pardo-Hernandez, R. Brian Haynes, Laura Martínez García, Tamara Navarro, Holger Schünemann and Pablo Alonso-Coello

    Citation: Health and Quality of Life Outcomes 2017 15:126

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  25. Content type: Research

    This paper investigates the properties and performance of the two generic measures, EQ-5D and SF-12, for Health-Related Quality of Life (HRQoL) assessments of pregnant women living with HIV in Kunming City, Yi...

    Authors: Xiaowen Wang, Guangping Guo, Ling Zhou, Jiarui Zheng, Xiumin Liang, Zhanqin Li, Hongzhuan Luo, Yuyan Yang, Liyuan Yang, Ting Tan, Jun Yu and Lin Lu

    Citation: Health and Quality of Life Outcomes 2017 15:158

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  26. Content type: Research

    Due to increasing export of labor service, many children following their parents leave from rural areas to urban areas in China. These migrant children might have psychological stress and lower quality of life...

    Authors: Fengjiao Xu, Haiyan Xing, Wei Yu, Sanmei Chen and Hui Li

    Citation: Health and Quality of Life Outcomes 2017 15:100

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  27. Content type: Research

    There are diverse opinions and confusion about defining and including patient values and preferences (i.e. the importance people place on the health outcomes) in the guideline development processes. This artic...

    Authors: Yuan Zhang, Pablo Alonso Coello, Jan Brożek, Wojtek Wiercioch, Itziar Etxeandia-Ikobaltzeta, Elie A. Akl, Joerg J. Meerpohl, Waleed Alhazzani, Alonso Carrasco-Labra, Rebecca L. Morgan, Reem A. Mustafa, John J. Riva, Ainsley Moore, Juan José Yepes-Nuñez, Carlos Cuello-Garcia, Zulfa AlRayees…

    Citation: Health and Quality of Life Outcomes 2017 15:52

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