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Graefe's Ophthalmology Cases

Edited by: 
Tina Dietrich (Berlin, Germany),
Cecilia Fenerty (Manchester, UK),
Andreas Stahl (Freiburg, Germany) and
Amira Stylianides (Liverpool, UK).

In partnership with Graefe's Archive for Clinical and Experimental Ophthalmology, one of the leading journals in clinical ophthalmology, this collection aims to publish reports on interesting and unexpected cases in the entire range of ophthalmology. Preference is given to case reports that shed new light on the pathogenesis, diagnosis or treatment of ophthalmic conditions. We hope the findings shared here will help in developing research in the field of ophthalmology.

This article collection is published in Journal of Medical Case Reports.

  1. Extragonadal germ cell tumor (EGCT) is a relatively rare condition, reportedly representing 3–7% of all germ cell tumors. We report a patient who had metachronous testicular tumor with uncommon metastases 20 y...

    Authors: Motoi Tobiume, Shigeyuki Aoki, Genya Nishikawa, Hiroyuki Muramatsu, Kenzo Ono, Shingo Morinaga, Koji Hara, Natsuko Ando, Keiko Ono, Chie Nishibata, Ayumi Hidano, Makiko Nakagawa, Ikumi Takahashi, Kanae Matsubara and Yoshiaki Yamada
    Citation: Journal of Medical Case Reports 2021 15:59
    Content type: Case report Published on:

  2. Hyperreflective lesions at the level of ganglion cell (GCL) and inner plexiform retinal layers (IPL) by optical coherence tomography (OCT) and cotton wool spots in the examination of the eye fundus have recent...

    Authors: José M. Ortiz-Egea, Jorge Ruiz-Medrano and José M. Ruiz-Moreno
    Citation: Journal of Medical Case Reports 2021 15:15
    Content type: Case report Published on:

  3. Developmental disorder and dementia in older adults have been considered unrelated clinical entities because their timing of diagnosis differs greatly; however, recent studies have suggested an association bet...

    Authors: Masahiko Takaya, Kazunari Ishii, Kaori Kiguchi, Kazumasa Saigoh and Osamu Shirakawa
    Citation: Journal of Medical Case Reports 2020 14:139
    Content type: Case report Published on:

  4. Mammary Paget’s disease is an eczematous eruption on the nipple and areola with underlying breast malignancy. It is often misinterpreted as chronic dermatitis or psoriasis causing a delayed diagnosis. Synchron...

    Authors: Lina Choridah, Wida Kartika Sari, Ery Kus Dwianingsih, Irianiwati Widodo, Suwardjo and Sumadi Lukman Anwar
    Citation: Journal of Medical Case Reports 2020 14:119
    Content type: Case report Published on:

  5. Extra-gastric (particularly colonic) lymphoma of mucosa-associated lymphoid tissue in the immunosuppressed solid organ transplant recipient is rare. We report a case of low-volume mucosa-associated lymphoid ti...

    Authors: Kylie Martin, Andrew Taylor, Constantine Tam, Prue Hill, David Machet and David Goodman
    Citation: Journal of Medical Case Reports 2020 14:81
    Content type: Case report Published on:

  6. Breast cancer is the most common cancer in women. However, in the management of breast cancer, paraneoplastic neurological syndromes represent a diagnostic and therapeutic challenge. The diagnosis of paraneopl...

    Authors: Giuseppe Sena, Gaetano Gallo, Giuseppina Vescio, Denise Gambardella, Stefano de Franciscis and Mariuccia Renne
    Citation: Journal of Medical Case Reports 2020 14:67
    Content type: Case report Published on:

  7. Proteinase 3-antineutrophil cytoplasmic antibody has been reported to be positive in 5–10% of cases of renal injury complicated by infective endocarditis; however, histological findings have rarely been report...

    Authors: Katsunori Yanai, Yoshio Kaku, Keiji Hirai, Shohei Kaneko, Saori Minato, Yuko Mutsuyoshi, Hiroki Ishii, Taisuke Kitano, Mitsutoshi Shindo, Haruhisa Miyazawa, Kiyonori Ito, Yuichiro Ueda, Masahiro Hiruta, Susumu Ookawara, Yoshihiko Ueda and Yoshiyuki Morishita
    Citation: Journal of Medical Case Reports 2019 13:356
    Content type: Case report Published on:

  8. Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur.

    Authors: Maria Cristina Savastano, Marco Rispoli and Bruno Lumbroso
    Citation: Journal of Medical Case Reports 2019 13:274
    Content type: Case report Published on:

  9. Avascular necrosis of the femoral capital epiphysis is the most serious complication after traumatic dislocation of the hip in children. This case report discusses the localization and revascularization of the...

    Authors: Kenta Momii, Satoshi Hamai, Goro Motomura, Kensuke Kubota, Masato Kiyohara, Takuaki Yamamoto and Yasuharu Nakashima
    Citation: Journal of Medical Case Reports 2019 13:254
    Content type: Case report Published on:

  10. Gonioscopy-assisted transluminal trabeculectomy is a novel and useful technique for ab interno trabeculotomy. However, gonioscopy-assisted transluminal trabeculectomy is difficult to perform in patients with c...

    Authors: Isao Nakao, Tadashi Mine, Mika Sakaguchi and Hiroshi Enaida
    Citation: Journal of Medical Case Reports 2019 13:249
    Content type: Case report Published on:

  13. Metastatic tumors in the orbit, especially from gastric cancer, are rare. We present a rare case of extraocular muscle metastasis from gastric cancer and raise consideration of metastasis to extraocular muscle...

    Authors: Sakiko Goto, Hiroaki Takeda, Yuriko Sasahara, Imi Takanashi and Hidetoshi Yamashita
    Citation: Journal of Medical Case Reports 2019 13:107
    Content type: Case report Published on:

  14. Vascular closure devices have been widely used to achieve rapid hemostasis after percutaneous catheterization procedures via the common femoral artery. The EXOSEAL vascular closure device is a device that can ...

    Authors: Ryota Urata, Tetsuya Nomura, Yusuke Hori, Kenichi Yoshioka, Hiroshi Kubota, Daisuke Miyawaki, Takeshi Sugimoto, Masakazu Kikai, Natsuya Keira and Tetsuya Tatsumi
    Citation: Journal of Medical Case Reports 2019 13:90
    Content type: Case report Published on:

  15. Malignant peritoneal mesothelioma is a rare aggressive tumor of the peritoneum. We report a rare case of resection of multiple localized malignant peritoneal mesotheliomas.

    Authors: Takashi Miyata, Yuta Fujiwara, Koji Nishijima, Fumio Futagami, Takashi Nakamura and Hiroyuki Takamura
    Citation: Journal of Medical Case Reports 2019 13:66
    Content type: Case report Published on:

  18. Trousseau syndrome is known as a variant of cancer-associated thrombosis. Trousseau syndrome commonly occurs in patients with lung or prostate cancer. Hypercoagulability is thought to be initiated by mucins pr...

    Authors: Ken-ichi Aoyama, Masashi Tamura, Masahiro Uchibori, Yasuhiro Nakanishi, Toshihiro Arai, Takayuki Aoki, Yuko Osawa, Akihiro Kaneko and Yoshihide Ota
    Citation: Journal of Medical Case Reports 2019 13:26
    Content type: Case report Published on:

  19. In this report, we present the results of a severe case of Sjögren’s syndrome-related keratopathy after fluocinolone acetonide 190-μg intravitreal implant (Iluvien®; Alimera Sciences Inc.) therapy.

    Authors: Joanna Wasielica-Poslednik, Norbert Pfeiffer and Adrian Gericke
    Citation: Journal of Medical Case Reports 2019 13:21
    Content type: Case report Published on:

  20. Ophthalmologists and retina specialists may consider choroidal detachment if patients with rhegmatogenous retinal detachment present with choroidal elevation. That misdiagnosis may lead to inappropriate treatm...

    Authors: Satoru Kase, Yuka Suimon, Kan Ishijima and Susumu Ishida
    Citation: Journal of Medical Case Reports 2018 12:389
    Content type: Case report Published on:

  21. Ibrutinib is a tyrosine kinase inhibitor commonly used in patients with chronic lymphocytic leukemia. Based on the published literature, it has a very sound ophthalmologic safety profile. In the following, we ...

    Authors: Anton M. Kolomeyer, Christopher K. Hwang and Benjamin J. Kim
    Citation: Journal of Medical Case Reports 2018 12:349
    Content type: Case report Published on:

  22. Poland syndrome is a congenital malformation characterized by ipsilateral hand and chest wall depression, including an absence or hypoplasia of the breast and pectoral muscles. These hypoplastic defects are re...

    Authors: Kenji Gonda, Yosuke Tachiya, Yuichi Hatakeyama, Tomoyuki Momma, Tomoko Tamaoki, Yuko Maejima, Yuichi Rokkaku, Shigehira Saji, Kenju Shimomura and Koji Kono
    Citation: Journal of Medical Case Reports 2018 12:312
    Content type: Case report Published on:

  23. Neurosarcoidosis is a rare complication, and cranial neuropathy is the most frequent manifestation of this disease. However, few cohesive reports have discussed multiple cranial neuropathies in Japanese patien...

    Authors: Tomoko Ohno, Mami Ishihara, Etsuko Shibuya and Nobuhisa Mizuki
    Citation: Journal of Medical Case Reports 2018 12:307
    Content type: Case report Published on:

  24. Eales’ disease is a difficult to treat idiopathic form of retinal vasculitis. We present such a case with peculiar epidemiology in which the only efficient therapeutic approach in order to maintain functional ...

    Authors: Radu Ivanescu, Ciprian Ivanescu, Kai Januschowski and Augustin Ivanescu
    Citation: Journal of Medical Case Reports 2018 12:310
    Content type: Case report Published on:

  25. Trigeminal neuralgia is a rare cause of postoperative pain after ophthalmic surgery and has only been described twice in the international literature: one case of pain after vitrectomy with a crystalline lens ...

    Authors: María del Pilar Lucena, Federico Furno Sola, Mitzy E. Torres Soriano and Fanny Andrea Gerster
    Citation: Journal of Medical Case Reports 2018 12:256
    Content type: Case report Published on:

  26. Proliferative diabetic retinopathy is a major cause of visual impairment in working-age adults worldwide. Panretinal photocoagulation is a cornerstone in its management; however, it may include a range of side...

    Authors: Patrik Schatz, Ahmed Aldayel, Ibrahim Taskintuna, Ehab Abdelkader and Marco Mura
    Citation: Journal of Medical Case Reports 2017 11:265
    Content type: Case report Published on: