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Glycoproteomics and Glycomics

Edited by Dr Punit Shah & Dr Hui Zhang

Clinical Proteomics published the Glycoproteomics and glycomics thematic series with both solicited and unsolicited content on the topic of protein glycosylation; one of the most common protein modifications in both normal biological processes and diseases. The series focusses on glycoproteomic or glycomic methods and their clinical applications. For further information or to make a pre-submission enquiry, please contact

For previous publications on the topic of glycoproteomics in Clinical Proteomics, you may like to refer to volume 4 which can be accessed via the SpringerLink website.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest Editors declare no competing interests.

  1. Research

    Analysis of age and gender associated N-glycoproteome in human whole saliva

    Glycoproteins comprise a large portion of the salivary proteome and have great potential for biomarker discovery and disease diagnosis. However, the rate of production and the concentration of whole saliva cha...

    Shisheng Sun, Fei Zhao, Qinzhe Wang, Yaogang Zhong, Tanxi Cai, Peng Wu, Fuquan Yang and Zheng Li

    Clinical Proteomics 2014 11:25

    Published on: 5 June 2014

  2. Review

    Nanotechnologies in Glycoproteomics

    Protein glycosylation, as an important post-translational modification, is implicated in a number of ailments. Applying proteomic approaches, including mass spectrometry (MS) analyses that have played a signif...

    Hu Zhao, Yaojun Li and Ye Hu

    Clinical Proteomics 2014 11:21

    Published on: 13 May 2014

  3. Review

    Glycoproteomic and glycomic databases

    Protein glycosylation serves critical roles in the cellular and biological processes of many organisms. Aberrant glycosylation has been associated with many illnesses such as hereditary and chronic diseases li...

    Deniz Baycin Hizal, Daniel Wolozny, Joseph Colao, Elena Jacobson, Yuan Tian, Sharon S Krag, Michael J Betenbaugh and Hui Zhang

    Clinical Proteomics 2014 11:15

    Published on: 13 April 2014

  4. Research

    Comprehensive profiling of accessible surface glycans of mammalian sperm using a lectin microarray

    It is well known that cell surface glycans or glycocalyx play important roles in sperm motility, maturation and fertilization. A comprehensive profile of the sperm surface glycans will greatly facilitate both ...

    Ai-Jie Xin, Li Cheng, Hua Diao, Peng Wang, Yi-Hua Gu, Bin Wu, Yan-Cheng Wu, Guo-Wu Chen, Shu-Min Zhou, Shu-Juan Guo, Hui-Juan Shi and Sheng-Ce Tao

    Clinical Proteomics 2014 11:10

    Published on: 16 March 2014

  5. Research

    Glycoproteomic analysis identifies human glycoproteins secreted from HIV latently infected T cells and reveals their presence in HIV+ plasma

    Glycoproteins secreted into plasma from T cells infected with human immunodeficiency virus (HIV) latent infection may provide insight into understanding the host response to HIV infection in vivo. Glycoproteomics...

    Weiming Yang, Jian-Ying Zhou, Li Chen, Minghui Ao, Shisheng Sun, Paul Aiyetan, Antoine Simmons, Hui Zhang and Jay Brooks Jackson

    Clinical Proteomics 2014 11:9

    Published on: 6 March 2014

  6. Review

    O-GlcNAc profiling: from proteins to proteomes

    O-linked β-D-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) onto serine and threonine residues of proteins is an important post-translational modification (PTM), which is involved in many crucial b...

    Junfeng Ma and Gerald W Hart

    Clinical Proteomics 2014 11:8

    Published on: 5 March 2014