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Microbial glycobiotechnology

Guest Editors: Professor Vijai Kumar Gupta, Scotland's Rural College, UK; Professor Ashok Pandey, CSIR-Indian Institute of Toxicology Research.

The Editor-in-Chief of Microbial Cell Factories, Prof Grzegorz Wegrzyn and the guest editors present a special collection with a thematic scheme: ‘Microbial Glycobiotechnology’.

The collection features contributions from the BRSI2020 conference and was also open to all.

Research and technologies involving carbohydrates to carbohydrate-based materials and the conversion of carbohydrates for renewable energy, agri and health fall under the umbrella of glycobiotechnology. Microbial glycobiotechnology refers to sustainable bioprocesses for the bioconversion of carbohydrates through microbial enzymes and microbial technologies, and the generation of tailor-made carbohydrate bioproducts/polymers for variety of novel applications in, bioenergy and fuels, biomaterials, in food and nutrition, and pharmaceuticals.

Topics of interest include, but are not limited to, the following:

  • Glycan biosynthesis
  • Glyco-enzymology
  • Modification of complex carbohydrates and their corresponding glycoconjugates including glycans, glycoproteins, glycolipids’
  • Biological functions of glycoconjugates and glycolipids

This collection is now closed to new submissions.

New Content Item


  1. Poultry is the world's most popular animal-based food and global production has tripled in the past 20 years alone. Low-cost vaccines that can be combined to protect poultry against multiple infections are a c...

    Authors: Marta Mauri, Thippeswamy H. Sannasiddappa, Prerna Vohra, Ricardo Corona-Torres, Alexander A. Smith, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Sherif Abouelhadid, Mark P. Stevens, Andrew J. Grant, Jon Cuccui and Brendan W. Wren

    Citation: Microbial Cell Factories 2021 20:193

    Content type: Research

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  2. Biodiesel is an eco-friendly and renewable energy source and a valuable substitute for petro-diesel. Sago processing wastewater (SWW), a by-product of the cassava processing industry, has starch content rangin...

    Authors: Kiruthika Thangavelu, Pugalendhi Sundararaju, Naganandhini Srinivasan and Sivakumar Uthandi

    Citation: Microbial Cell Factories 2021 20:167

    Content type: Research

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  3. Microalgae has the capability to replace petroleum-based fuels and is a promising option as an energy feedstock because of its fast growth, high photosynthetic capacity and remarkable ability to store energy r...

    Authors: Ranjna Sirohi, Jaemin Joun, Hong II Choi, Vivek Kumar Gaur and Sang Jun Sim

    Citation: Microbial Cell Factories 2021 20:163

    Content type: Review

    Published on:

  4. Sulfate modification of N-glycans is important for several biological functions such as clearance of pituitary hormones or immunoregulation. Yet, the prevalence of this N-glycan modification and its functions rem...

    Authors: Léa Chuzel, Samantha L. Fossa, Madison L. Boisvert, Samanta Cajic, René Hennig, Mehul B. Ganatra, Udo Reichl, Erdmann Rapp and Christopher H. Taron

    Citation: Microbial Cell Factories 2021 20:162

    Content type: Research

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  5. The fungal cell wall is an essential and robust external structure that protects the cell from the environment. It is mainly composed of polysaccharides with different functions, some of which are necessary fo...

    Authors: Vanessa S. D. Carvalho, Laura Gómez-Delgado, M. Ángeles Curto, M. Belén Moreno, Pilar Pérez, Juan Carlos Ribas and Juan Carlos G. Cortés

    Citation: Microbial Cell Factories 2021 20:126

    Content type: Technical Notes

    Published on:

  6. The manufacture of recombinant therapeutics is a fastest-developing section of therapeutic pharmaceuticals and presently plays a significant role in disease management. Yeasts are established eukaryotic host f...

    Authors: Aravind Madhavan, K. B. Arun, Raveendran Sindhu, Jayaram Krishnamoorthy, R. Reshmy, Ranjna Sirohi, Arivalagan Pugazhendi, Mukesh Kumar Awasthi, George Szakacs and Parameswaran Binod

    Citation: Microbial Cell Factories 2021 20:124

    Content type: Review

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  7. Human milk is the gold standard for nutrition of infant growth, whose nutritional value is mainly attributed to human milk oligosaccharides (HMOs). HMOs, the third most abundant component of human milk after l...

    Authors: Shunhao Zhang, Tianle Li, Jing Xie, Demao Zhang, Caixia Pi, Lingyun Zhou and Wenbin Yang

    Citation: Microbial Cell Factories 2021 20:108

    Content type: Review

    Published on:

    The Correction to this article has been published in Microbial Cell Factories 2021 20:140

  8. Protein Glycan Coupling Technology (PGCT) uses purposely modified bacterial cells to produce recombinant glycoconjugate vaccines. This vaccine platform holds great potential in this context, namely due to its ...

    Authors: Jasmin J. Samaras, Marta Mauri, Emily J. Kay, Brendan W. Wren and Martina Micheletti

    Citation: Microbial Cell Factories 2021 20:104

    Content type: Research

    Published on:

  9. Glucosylglycerol (2-O-α-d-glucosyl-sn-glycerol; GG) is a natural osmolyte from bacteria and plants. It has promising applications as cosmetic and food-and-feed ingredient. Due to its natural scarcity, GG must be ...

    Authors: Katharina N. Schwaiger, Monika Cserjan-Puschmann, Gerald Striedner and Bernd Nidetzky

    Citation: Microbial Cell Factories 2021 20:79

    Content type: Research

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  10. The large-scale application of organic pollutants (OPs) has contaminated the air, soil, and water. Persistent OPs enter the food supply chain and create several hazardous effects on living systems. Thus, there...

    Authors: Pankaj Bhatt, Amit Verma, Saurabh Gangola, Geeta Bhandari and Shaohua Chen

    Citation: Microbial Cell Factories 2021 20:72

    Content type: Review

    Published on:

  11. The accelerating energy demands of the increasing global population and industrialization has become a matter of great concern all over the globe. In the present scenario, the world is witnessing a considerabl...

    Authors: Praveen C. Ramamurthy, Simranjeet Singh, Dhriti Kapoor, Parul Parihar, Jastin Samuel, Ram Prasad, Alok Kumar and Joginder Singh

    Citation: Microbial Cell Factories 2021 20:55

    Content type: Review

    Published on:

  12. Humic substances (HS) form the largest proportion among all the constituents of soil organic matter and are a key component of the terrestrial ecosystem. HS plays a multifunctional role in the environment by c...

    Authors: Iniyakumar Muniraj, Syed Shameer, Priyadharshini Ramachandran and Sivakumar Uthandi

    Citation: Microbial Cell Factories 2021 20:48

    Content type: Research

    Published on:

  13. Alzheimer’s disease (AD) is a chronic neurodegenerative disease associated with the overproduction and accumulation of amyloid-β peptide and hyperphosphorylation of tau proteins in the brain. Despite extensive...

    Authors: Dana Vigasova, Michal Nemergut, Barbora Liskova and Jiri Damborsky

    Citation: Microbial Cell Factories 2021 20:25

    Content type: Review

    Published on:

  14. Lactic acid bacteria can synthesize dextran and oligosaccharides with different functionality, depending on the strain and fermentation conditions. As natural structure-forming agent, dextran has proven useful...

    Authors: Prabin Koirala, Ndegwa Henry Maina, Hanna Nihtilä, Kati Katina and Rossana Coda

    Citation: Microbial Cell Factories 2021 20:23

    Content type: Research

    Published on:

  15. Many fungi grow as saprobic organisms and obtain nutrients from a wide range of dead organic materials. Among saprobes, fungal species that grow on wood or in polluted environments have evolved prolific mechan...

    Authors: Michael Dare Asemoloye, Mario Andrea Marchisio, Vijai Kumar Gupta and Lorenzo Pecoraro

    Citation: Microbial Cell Factories 2021 20:20

    Content type: Review

    Published on:

  16. Rhamnolipids (RLs) are surface-active compounds and belong to the class of glycolipid biosurfactants, mainly produced from Pseudomonas aeruginosa. Due to their non-toxicity, high biodegradability, low surface ten...

    Authors: Priyanka Thakur, Neeraj K. Saini, Vijay Kumar Thakur, Vijai Kumar Gupta, Reena V. Saini and Adesh K. Saini

    Citation: Microbial Cell Factories 2021 20:1

    Content type: Review

    Published on:

  17. Nerol (C10H18O), an acyclic monoterpene, naturally presents in plant essential oils, and is used widely in food, cosmetics and pharmaceuticals as the valuable fragrance. Meanwhile, chemical synthesis is the only ...

    Authors: Xueyan Mo, Xinghua Cai, Qinyan Hui, Huijie Sun, Ran Yu, Ru Bu, Bing Yan, Qian Ou, Quanwen Li, Sheng He and Chengjian Jiang

    Citation: Microbial Cell Factories 2021 20:4

    Content type: Research

    Published on: