Advances in genome editing technology and its promising applications have had a great impact on basic science and clinical research. A number of approaches to genome editing have been developed. Particularly the CRISPR/Cas system, has given scientists the ability to make precise changes in the genomes ranging from plants to animals. In addition, CRISPR-based base editing and epigenetic editing greatly expand the genome editing toolbox.
Here we present a collection of articles on genome editing in plant and animal cell systems that have been pulled together from manuscripts published in BMC Biotechnology and BMC Plant Biology submitted to a thematic series call for papers that drew to a close in late 2019. This collection highlights the latest in genome editing technologies and tools available to manipulate genomes to affect change to cellular behavior as well as whole organism phenotypes.