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Genome Stability

  1. Content type: Review

    Human cancers results in large part from the accumulation of multiple mutations. The progression of premalignant cells is an evolutionary process in which mutations provide the fundamental driving force for ge...

    Authors: Jun Zou, Chen Wang, Xiangyi Ma, Edward Wang and Guang Peng

    Citation: Cell & Bioscience 2017 7:29

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  2. Content type: Review

    Persistent dysregulation of the DNA damage response and repair in cells causes genomic instability. The resulting genetic changes permit alterations in growth and proliferation observed in virtually all cancer...

    Authors: Anna Palovcak, Wenjun Liu, Fenghua Yuan and Yanbin Zhang

    Citation: Cell & Bioscience 2017 7:8

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  3. Content type: Review

    The addition of mono-ubiquitin or poly-ubiquitin chain to signaling proteins in response to DNA damage signal is thought to be a critical event that facilitates the recognition of DNA damage lesion site, the a...

    Authors: Mingjing He, Zhuan Zhou, Anil A. Shah, Haojing Zou, Jin Tao, Qianming Chen and Yong Wan

    Citation: Cell & Bioscience 2016 6:62

    Published on: