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Gastric Cancer Awareness Month

Explore our curated collection of gastric cancer research in honor of Gastric Cancer Awareness Month this November. This collection of research and review papers highlights the latest advances in detection, genetics, and treatment. These open access articles reflect the evolving landscape of gastric cancer research, offering hope for a brighter future in the fight against this disease.

The following journals are included in this collection: Biomarker Research, Cancer Cell International, Cancer Imaging, Experimental Hematology & Oncology, Journal of Experimental and Clinical Cancer Research, Journal of Hematology & Oncology, and Molecular Cancer.

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  1. Recent advances in circulating cell-free DNA (cfDNA) analysis from biofluids have opened new avenues for liquid biopsy (LB). However, current cfDNA LB assays are limited by the availability of existing informa...

    Authors: Neeti Swarup, Jordan Cheng, Irene Choi, You Jeong Heo, Misagh Kordi, Mohammad Aziz, Akanksha Arora, Feng Li, David Chia, Fang Wei, David Elashoff, Liying Zhang, Sung Kim, Yong Kim and David T.W. Wong
    Citation: Biomarker Research 2023 11:90
    Content type: Research Published on:

    The Correction to this article has been published in Biomarker Research 2023 11:96

  2. To build and validate a radiomics nomogram based on preoperative CT scans and clinical data for detecting synchronous ovarian metastasis (SOM) in female gastric cancer (GC) cases.

    Authors: Qian-Wen Zhang, Pan-Pan Yang, Yong-Jun-Yi Gao, Zhi-Hui Li, Yuan Yuan, Si-Jie Li, Shao-Feng Duan, Cheng-Wei Shao, Qiang Hao, Yong Lu, Qi Chen and Fu Shen
    Citation: Cancer Imaging 2023 23:71
    Content type: Research article Published on:

  4. Advanced gastric cancer (GC) is a lethal malignancy, harboring recurrent alterations in cell cycle pathway, especially the CDKN2A-CDK4/CDK6/CCND1 axis. However, monotherapy of CDK4/6 inhibitors has shown limit...

    Authors: Mei Feng, Hao Xu, Wenyuan Zhou and Yisheng Pan
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:44
    Content type: Research Published on:

  5. N4-acetylcytidine (ac4C), a widespread modification in human mRNAs that is catalyzed by the N-acetyltransferase 10 (NAT10) enzyme, plays an important role in promoting mRNA stability and translation. However, ...

    Authors: Min Deng, Long Zhang, Wenying Zheng, Jiale Chen, Nan Du, Meiqi Li, Weiqing Chen, Yonghong Huang, Ning Zeng, Yuanbin Song and Yongming Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:9
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:98

  6. Liver metastasis (LM) is a major obstacle to the prognosis of gastric cancer (GC) patients, but the molecular mechanism underlying gastric cancer liver metastasis (GC-LM) remains unknown. Exosomes have been id...

    Authors: Shengkui Qiu, Li Xie, Chen Lu, Chao Gu, Yiwen Xia, Jialun Lv, Zhe Xuan, Lang Fang, Jing Yang, Lu Zhang, Zheng Li, Weizhi Wang, Hao Xu, Bowen Li and Zekuan Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:296
    Content type: Research Published on:

  7. Recently, the global incidence of gastric/gastroesophageal junction (G/GEJ) cancer has remained high. China is also a large country with a high gastric cancer (GC) incidence rate, where the cases of GC account...

    Authors: Weiling Li, Xiaoling Zhang, Yunyi Du, Ying Zhang, Jing Lu, Wenqing Hu and Jun Zhao
    Citation: Biomarker Research 2022 10:71
    Content type: Review Published on:

  8. Gastric cancer is characterized by high morbidity and mortality worldwide. Early-stage gastric cancer is mainly treated with surgery, while for advanced gastric cancer, the current treatment options remain ins...

    Authors: Hongzhen Cai, Man Li, Ruiyi Deng, Mopei Wang and Yanyan Shi
    Citation: Biomarker Research 2022 10:67
    Content type: Review Published on:

  9. The Hippo pathway functions as a tumor suppressor pathway in human cancers, while dysfunction of the Hippo pathway is frequently observed in malignancies. Although YAP/TAZ activity is tightly controlled by the...

    Authors: Dehai Wang, Zhongbo Li, Xin Li, Cheng Yan, Huijie Yang, Ting Zhuang, Xiao Wang, Yifeng Zang, Ziping Liu, Tianshi Wang, Rixia Jiang, Peng Su, Jian Zhu and Yinlu Ding
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:219
    Content type: Research Published on:

  10. Gastric cancer (GC) is an aggressive malignancy with a high mortality rate and poor prognosis, primarily caused by metastatic lesions. Improved understanding of GC metastasis at the molecular level yields mean...

    Authors: Xiaolin Wang, Jiahui Zhang, Guozhen Cao, Jinghan Hua, Ge Shan and Wenchu Lin
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:218
    Content type: Review Published on:

  12. Thrombospondin-2 (THBS2) is a versatile glycoprotein that regulates numerous biological functions, including the apoptosis-proliferation balance in endothelial cells, and it has been linked to tumor angiogenes...

    Authors: Xingchen Liao, Wei Wang, Baoping Yu and Shiyun Tan
    Citation: Cancer Cell International 2022 22:213
    Content type: Research Published on:

  13. Hypoxia and inflammation tumor microenvironment (TME) play a crucial role in tumor development and progression. Although increased understanding of TME contributed to gastric cancer (GC) progression and progno...

    Authors: Haiyan Piao, Lingfeng Fu, Yuxin Wang, Yang Liu, Yue Wang, Xiangyu Meng, Dong Yang, Xiang Xiao and Jun Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:174
    Content type: Research Published on:

  14. Histone lysine-specific demethylase 1 (LSD1) expression has been shown to be significantly elevated in gastric cancer (GC) and may be associated with the proliferation and metastasis of GC. It has been reporte...

    Authors: Dan-Dan Shen, Jing-Ru Pang, Ya-Ping Bi, Long-Fei Zhao, Yin-Rui Li, Li-Juan Zhao, Ya Gao, Bo Wang, Ning Wang, Liuya Wei, Huiqin Guo, Hong-Min Liu and Yi-Chao Zheng
    Citation: Molecular Cancer 2022 21:75
    Content type: Research Published on:

  16. N6-methyladenosine (m6A) RNA methylation and circular RNAs (circRNAs) have been shown to act vital roles in multiple malignancies including gastric cancer (GC). However, there is little knowledge about how m6A mo...

    Authors: Hui-Ning Fan, Zhao-Yu Chen, Xiao-Yu Chen, Ming Chen, You-Cai Yi, Jin-Shui Zhu and Jing Zhang
    Citation: Molecular Cancer 2022 21:51
    Content type: Research Published on:

  17. Majority of gastric cancers (GC) are diagnosed at advanced stages which contributes towards their poor prognosis. In view of this clinical challenge, identification of non-invasive biomarker for early diagnosi...

    Authors: Souvick Roy, Mitsuro Kanda, Sachiyo Nomura, Zhongxu Zhu, Yuji Toiyama, Akinobu Taketomi, James Goldenring, Hideo Baba, Yasuhiro Kodera and Ajay Goel
    Citation: Molecular Cancer 2022 21:42
    Content type: Research Published on:

  18. Gastric cancer (GC) is one of the most pernicious tumors that seriously harm human healthcare. GC metastasis is one of the prime cause of failed cancer treatment, but correlation between N6-methyladenosine (m6...

    Authors: Yiyang Hu, Chunli Gong, Zhibin Li, Jiao Liu, Yang Chen, Yu Huang, Qiang Luo, Sumin Wang, Yu Hou, Shiming Yang and Yufeng Xiao
    Citation: Molecular Cancer 2022 21:34
    Content type: Research Published on:

  19. Gastric cancer (GC) has a poor prognosis and limited therapeutic options. As a new promising cancer therapeutic approach, chimeric antigen receptor (CAR)-T cells represent a potential GC treatment. We investig...

    Authors: Fengqiang Sun, Xiaomei Yu, Ruixue Ju, Zhanzhao Wang and Yuhui Wang
    Citation: Cancer Cell International 2022 22:50
    Content type: Primary research Published on: