Frontiers in inflammation-associated tumorigenesis and metastasis

Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells

For all living organisms, the adaptation to outside environments is an essential determinant to survive natural and artificial selections and to sustain the whole ecosystem intact with functional biodiversity....

Authors: Kouichi Tabu and Tetsuya Taga

Citation: Inflammation and Regeneration 2022 42:54

Content type: Review Published on: 30 November 2022
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Inflammation-associated premetastatic niche formation

Metastasis remains the leading cause of cancer-related death. In 1889, Stephen Paget originally proposed the theory “seed-and-soil.” Both cancer cell-intrinsic properties (“seed”) and fertile microenvironment ...

Authors: Atsuko Deguchi and Yoshiro Maru

Citation: Inflammation and Regeneration 2022 42:22

Content type: Review Published on: 3 July 2022
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The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?

Cellular senescence is a state of irreversible cell cycle arrest that can be induced by a variety of potentially oncogenic stimuli, including DNA damage. Hence, senescence has long been considered to suppress ...

Authors: Naoko Ohtani

Citation: Inflammation and Regeneration 2022 42:11

Content type: Review Published on: 2 April 2022
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