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Epigenetics in stem cells and cancer

Tumorigenesis can be regarded as a progress of ‘reprogramming’ normal cells into an uncontrolled status via many genetic and epigenetic changes. Emerging evidence suggests that cancer cells use similar epigenetic alterations that occur during stem cell differentiation. This series summarizes the epigenetic events in cancer and stem cells and tries to stimulate the discussion on the concept of ‘cancer stem cells’.

Dr Jing Huang

  1. Content type: Review

    Adult stem cells maintain tissue homeostasis by their ability to both self-renew and differentiate to distinct cell types. Multiple signaling pathways have been shown to play essential roles as extrinsic cues ...

    Authors: Lama Tarayrah and Xin Chen

    Citation: Cell & Bioscience 2013 3:41

    Published on:

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