Genome Biology is calling for submissions to our Collection on epistatic effects.
Epistasis plays a crucial role in shaping the genetic architecture of complex traits. Understanding how gene interactions influence these traits enables more accurate genetic mapping and it enhances our grasp of genetic networks, evolutionary dynamics, and the precision of genomic predictions in personalized medicine. Additionally, research on epistasis informs synthetic biology and genetic engineering by clarifying how gene interactions affect system behavior.
This collection welcomes submissions on:
- Genome-wide detection of epistatic interactions
- Epistasis in complex diseases
- Methodological advancements in epistasis analysis
- Integrative approaches for studying gene-gene interactions
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